Select all that apply.
Which of the following statements are true about the genetic disease phenylketonuria?
It is not tested for until a person has symptoms later in life.
Untreated phenylketonuria can lead to brain damage.
Phenylketonuria is effectively treated with gene therapy.
It requires lifelong treatment.
Prenatal surgery is used to treat it.

Answer:

Untreated phenylketonuria can lead to brain damage.

It requires lifelong treatment.

Explanation:

The statements that are true about the genetic disease phenylketonuria are:

-Untreated phenylketonuria can lead to brain damage.

-It requires lifelong treatment.

Phenylketonuria (PKU) is a rare genetic disorder that affects the metabolism of the amino acid phenylalanine. People with PKU are unable to properly break down phenylalanine, an amino acid found in many protein-rich foods, as a result, the amino acid and its by-product, phenylpyruvic acid (PPA) builds up to harmful levels in the body, leading to intellectual disability, behavioral problems, and other serious health problems. PKU is caused by a mutation in the gene that codes for the enzyme phenylalanine hydroxylase (PAH), which normally converts phenylalanine to tyrosine.

The disorder is inherited in an autosomal recessive pattern, which means that a person must inherit two copies of the mutated gene, one from each parent, to develop the condition. PKU is usually diagnosed soon after birth by newborn screening, it is not typically tested for until a person has symptoms later in life. The treatment for PKU is a low phenylalanine diet, it requires lifelong treatment.

Learn more about Phenylketonuria, here:

https://brainly.com/question/29237543

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