Both perforin and granzymes are essential for the effective and efficient killing of cells. They are found in cytotoxic t lymphocyte granules.
The protein perforin, often referred to as cytoplasmic granule toxins, is a pore-forming agent. The cytotoxic granules of cytotoxic lymphocytes include a family of structurally similar serine proteases known as Granzyme (CLs). Target-cell apoptosis is collaboratively induced by perforin and granzyme. Target cells must be properly supplied by perforin in order for granzyme to cause apoptosis to occur.
Granzyme's likelihood of passive diffusion is further reduced by the fact that both perforin and granzyme attach to the target-cell surface as a single macromolecular complex linked with serglycin. Granzymes A and B's roles in triggering target-cell death have undergone significant in vitro research, and their molecular actions are more known than those of perforin.
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please help with tis i believe its attached below due in 3 days MRS>COGLIATIS CLASS
Answer:im pretty sure the answer is 3
Explanation:
look at the e,d postion
Answer: The post won't show.
Explanation:
Imagine a transmembrane molecule that lies in the plasma membrane and acts as a receptor for an extracellular signaling molecule. When the ligand-binding domain is inserted into the er during synthesis of this transmembrane molecule, will it lie on the lumen side of the er or the cytoplasm side?.
The ER lumen will contain the ligand-binding domain, which will also travel through the Golgi in the same direction.
The fusion protein-containing vesicle will leave the trans Golgi network in the last stage of transport and fuse with the plasma membrane, exposing the vesicle lumen to the outside of the cell.
Additionally, given that glycosylation occurs in the ER and Golgi lumen, any oligosaccharide subunits that may have been added to the protein will be found on its extracellular domain.
The other chemicals will be linked to peripheral proteins in an extracellular environment. Peripheral proteins can bind to other molecules even when they lack a transmembrane domain.
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Differences among individual members of a species are called_
A. fitness
B. natural selection
C. adaptations
D. variations
?
Answer:
D. variations
Explanation:
Differences among individual members of a species are called variations. Variations can refer to differences in physical characteristics, behaviors, or other traits that are present within a species. These variations can be inherited from parents or can arise through mutations or other changes in the genetic material of an individual.
Variations can be important for the process of natural selection, which is the process by which certain traits become more or less common in a population over time based on their impact on an individual's ability to survive and reproduce (fitness). Adaptations are traits that have evolved over time through natural selection and help an individual to better survive and reproduce in a particular environment.
Answer:
D. Variations.
Explanation:
Variation is defined as having any modification caused by environmental factors.
This is exemplified particularly in the Charles Darwin and the finches that he found at Galapagos Island, which essentially had 4 groups of finches with varying size beaks, from the smallest to largest:
1) Green Warbler Finch
2) Small Tree Finch
3) Medium Ground Finch
4) Large Ground Finch.
~
What is found is that, depending on the types of available food, a species may adapt towards eating that particular food source in an effort to keep oneself alive. Any useful traits, therefore, would be passed down through generations, while those who failed to adapt would die out.
However, it is important to note that while variation can be seen, and holds some truth to it, Darwinism theory as a whole is not scientific, as the layering of fossil records does not coincide with the theory itself. Evolution, if it was to have occurred, should evolve in such a way that organisms with similar characteristics should be found in order, rather than modifications found in multiple layers. It is also noteworthy that the Darwinist theory calls for only those who are able to adapt to be able to survive, and that unnecessary traits would, sooner or later, be dropped. However, this is not the case, particularly with humans, as humans take part in many leisurely activities that have no benefit towards one's own survival. Darwin's suggestion is that heritable traits that help organisms survive would be the only ones passed down, but humanity as an example shows that such ideas are in fact not true.
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some dried peas and beans, such as lentils, are nutrient-dense sources of folate. what other nutritional benefits do beans provide?
In addition to supporting many regular metabolic processes, iron and folate are crucial for preventing anaemias. For proper muscle and nerve function, you need potassium and magnesium.
What role do the nerves play that is most crucial?Your nervous system controls how your body functions. This system, which is based in your brain, regulates your movements, thoughts, and automatic responses to the surroundings. It also regulates other other body processes and systems, including digestion, breathing, and sexual development (puberty).
Which of the four kinds of nerves are they?Based on how they perform, the three different types or nerves inside the human body are divided. The nerve impulses, motor nerves, and mixed nerves are those.
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Experiments with genetically altered mice showed that the mice would consume abnormally high amounts of bitter-tasting compounds in water after their _____.
Experiments with genetically altered mice displayed that the mice consumed an unusually high amount of bitter taste compounds in water after their sweet taste cells were altered to express receptors for bitter tastants.
It was also deduced from this experiment that the sensation of taste depends solely on which taste cell is activated.
Studies using genetically modified mice showed that when their sweet taste cells was changed to produce receptors for bitter tastings, the animals drank an extraordinarily high amount of such bitter taste chemicals from water.
The expression of bitter taste buds in sweet-taste cells suggests that the taste perception is solely dependent on the taste cell that was stimulated.
The correct answer will be option (d).
The question is incomplete. the complete question is:-
Experiments with genetically altered mice displayed that the mice consumed an unusually high amount of bitter taste compounds in water after their:
(1) Hormone receptors for digestive hormones were removed or eliminated, displaying that bitter taste is strengthened by digestive responses,
(2) Salt taste cells were altered to express receptors for bitter tastants, proposing that animals have an uncontrolled appetite for salt,
(3) Visual sense was diminished or eliminated, proposing that mice grasp visual signals regarding bitter taste,
(4) Sweet taste cells were altered to express receptors for bitter tastants, proposing that the sensation of taste depends solely on which taste cell is activated.
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Which question, if investigated, would best lead to a better understanding of mendel’s law of independent assortment?a. Why did red hair phenotype skip a generation?b. Would other blonde haired individuals also have brown eyes?c. Why did the son inherit red hair form two brown haired parents?d. Which hair color is the dominant phenotype
The correct answer is:
b. Would other blonde haired individuals also have brown eyes?
Mendel's law of independent sorting states that inheritance of one trait is independent of inheritance of other traits. To better understand this law, we ask the following survey questions:
"How do different traits such as hair and eye color segregate and classify independently during gamete (sperm or egg) formation?"
We address the underlying mechanisms of independent sorting, which explain why we skip , or why individuals can inherit certain traits from their parents.
This means that the transmission of one genetic information for one trait, such as hair color, does not interfere with the transmission of genetic information for another trait, such as eye color.
To understand how this works, it helps to know genetics and how traits are passed on from parents to offspring. Our traits are determined by the genes we inherit from our parents. Each gene has different versions called alleles. For example, a gene that determines hair color may have different alleles for brown hair, blond hair, red hair, etc.
During sexual reproduction, gametes (sperm or eggs) produced by an individual contain only one copy of each gene. This is because gametes are formed through a process called meiosis, in which genetic material is separated from the parent cell into separate gametes. When gametes from two individuals come together to form a new individual, the resulting offspring have a combination of genes from both parents.
The way these genes are passed down from generation to generation is governed by the principles of Mendelian inheritance. One of these principles is the Law of Independent Assortment. This means that the transmission of genetic information for one trait, such as hair color, does not interfere with the transmission of genetic information for another trait, such as eye color.
For example, if someone with brown hair and brown eyes mates with someone with blonde hair and blue eyes, their offspring can have any combination of these traits. For example, brown hair and blue eyes, blonde and brown eyes, or blonde and blue eyes. The particular combination of traits an individual inherits is determined by which gametes of each parent come together during fertilization, and this process is random.
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pls help and ill mark brainly
Students are using cubes to model how surface area to volume ratio impacts cellular homeostasis. The students have created two models of equal size. Model A is one solid cube. Model B is a cube composed of nine smaller cubes. Each cube represents a cell. Which cube would have difficulty maintaining homeostasis?
A) Model A because the larger surface area to volume ratio of the cell makes moving
nutrients and waste into and out of the cell more difficult.
B) Model B because the smaller surface area to volume ratio of the cells makes
moving nutrients and waste into and out of the cells more difficult.
C) Model B because the larger surface area to volume ratio of the cells makes
moving nutrients and waste into and out of the cells more difficult.
D) Model A because the smaller surface area to volume ratio of the cell makes moving nutrients and waste into and out of the cell more difficult.
The cube that would have difficulty for maintaining homeostasis is Model A because the smaller surface area to volume ratio of the cell makes moving nutrients and waste into and out of the cell more difficult (Option D).
What is the cellular homeostatic state?The cellular homeostatic state refers to the state of internal equilibrium in the cell which is mainly due to the ability to perform all metabolic activities such as the intake of nutrients and elimination of waste products.
A higher number of smaller cell increase the surface volume cell ratio, thereby many cells have more chances to maintain homeostasis than a larger single cell.
Therefore, with this data, we can see that the cellular homeostatic state is based on a state of internal equilibrium which can be reached by having a suitable surface volume ratio in multicellular organisms.
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Which is most likely an example of a heat source?
1. Lake Ontario on a clear fall night
2. an iceberg in the North Atlantic Ocean
3. a desert waterhole on a sunny summer day
4. a Rocky Mountain glacier in August
Answer:
I feel its no. 3 a desert waterhole on a sunny summer day
Carotenoids always start out this color, then are changed by chemicals in the body to different colors. What colors do carotenoids produce?
Carotenoids always start out this color, then are changed by chemicals in the body to different colors. Carotenoids produce yellow, orange, red and purple colors.
More than 750 naturally occurring pigments belonging to the class of carotenoids are produced by plants, algae, and photosynthetic microorganisms . Many plants get their yellow, orange, and red colours from these vibrant chemicals. The majority of the 40 to 50 carotenoids contained in the human diet are found in fruits and vegetables.
Carotenoids are tetraterpene pigments that appear in yellow, orange, red, and purple hues. Carotenoids, which are present in algae, some types of fungi and archaea, plants, mammals, and photosynthetic bacteria, are responsible for the majority of the colours in nature.
Antioxidants called carotenoids are good for you since they can boost your immune system and keep you healthy. Vitamin A, which is necessary for growth, the health of the immune system, and the condition of the eyes, can be produced from provitamin A carotenoids.
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Cloud cover is the percent of Earth's surface covered by clouds! Cloud cover may increase due to an increase in cosmic ray flux (the number of high-energy particles from space that reaches Earth). Figure 1 shows the relationship between low cloud cover and relative cosmic ray flux (RCRF). What was the monthly average cloud cover in January of 1990?
a. 20.1%
b. 7%
c. 19.25%
d. 3.5%
Figure 1 shows the relationship between low cloud cover and relative cosmic ray flux (RCRF) therefore the monthly average cloud cover in January of 1990 is 20.1% and is therefore denoted as option A.
What is a Cloud?
This is referred to as a mass of water drops or ice crystals suspended in the atmosphere and they form when water condenses in the sky.
Cloud cover may increase due to an increase in cosmic ray flux in which the diagram shows the relationship between the two set of parameters in different time frame or periods.
From the diagram , we can deduce that the monthly average cloud cover in January of 1990 is 20.1% which is derived when the point is traced to the readings on the graph and is therefore the reason why option A was chosen aas the correct answer.
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In 1988, james hansen projected future warming trends. He used 3 different scenarios, identified as a, b, and c. Each represented different levels of greenhouse gas emissions. All three indicated a strong cause and effect relationship between observed temperatures and human emissions of greenhouse gases into the atmosphere. Greenhouse gas emissions are at the center of almost all climate change concerns. What are the likely effects of increasing greenhouse gas emissions on the ecosystem? select all that apply.
Answer:
extinction
Explanation:
depletion in some of the sources of energy
Which organic compounds are needed for the synthesis of the plasma membrane, contain a large amount of stored energy, and have been linked to cardiovascular diseases?.
The organic compounds that needed for the synthesis of the plasma membrane, contain a large amount of stored energy and linked to cardiovascular disease is LIPID.
Lipid and its functionLipid is an organic compound which is insoluble in water. It is including fats and oils (triglycerides), phospholipids, waxes and steroids. Each type of lipid contribute to some vital processes, however associated with a certain disease.
Lipids are an essential structure of the plasma membrane. According to the fluid mosaic model, the plasma membrane is a mosaic of carbohydrate, lipid and proteins. The plasma membrane require lipids as a semi-permeable barrier between a cell and its environment. There are 3 types of membrane lipid molecules : phospholipids, cholesterol and glycolipids. A phospholipid is made of glycerol, 2 fatty acid tails and phosphate-linked head group. These structures form two layers with its tails pointing inward because they are amphipathic. This arrangement called a phospholipid bilayer. Within the body, lipids function as an energy reserve. Lipid provide 9 calories per gram, so they contain more energy than carbohydrates or protein which has 4 calories per gram. That’s why low-fat diets are recommended for weight loss. Some of lipids are healthier than others. Like unsaturated fats, may provide some health benefits but saturated fats and trans fats are harmful to our health. Eating higher amount of this fats is linked to elevated LDL level which increases risk of cardiovascular disease.Learn more about cell membrane by clicking this linkhttps://brainly.com/question/14871353
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in guinea pigs, having black fur is a dominant trait. a student has a pet guinea pig with white fur. what can be concluded about the guinea pig?
The guinea pig received a dominant gene for black coat color from one parent and a recessive gene for white coat color from the other parent.
A gene is the fundamental physical and purposeful unit of heredity. Some genes act as instructions to make molecules referred to as proteins. But, many genes do now not code for proteins.
Our genes incorporate instructions that inform your cells to make molecules referred to as proteins. Proteins perform various features on our body to keep you healthy. Every gene includes commands that determine your functions, together with eye color, hair shade and height.
Few genes act as commands to make molecules referred to as proteins.In human beings, genes vary in length from a few hundred DNA bases to extra than 2 million bases.
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mary anne warren says that human lives have greater intrinsic value than animal lives because human lives are worth more to their possessors.
Compared to nonhuman animals, human life has a higher intrinsic value. Because their owners value human lives more, this is the case.
Warren contends that animal rights are inferior to human rights because people are intelligent while animals are not. is, everyone who is capable of feeling anything, such as feelings of happiness or fulfillment as well as pain, suffering, or annoyance.
In other words, they are traits that are "intrinsic" to the person rather than being influenced by their environment—the genetic, physiological, and pathological aspects of an individual are among these intrinsic factors.
Why are people considered to be morally superior to animals?Why should people have more moral standing than other animals? According to Immanuel Kant, a person's autonomy and rationality confer moral worth on them. The same idea was maintained by Aristotle. So maybe we have higher moral value than other creatures since we have autonomy and the ability to reason.
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in rwanda, there are more young children than teenagers, and more teenagers than adults. this age structure indicates a population that
In Rwanda, there are more young children than teenagers and also more teenagers than adults, then this age structure indicates a population that will double in 30 years.
What is the age structure of population?The age structure of a population is defined as the proportionate numbers of people in different age categories in a population for a defined time. It is a natural characteristic of a population in a region and the age structure is closely related to the birth rate, death rate and migration of a population.
Countries with lower median age have higher population growth rates. Lower-income countries have a lower median age.
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True or FalseHurricanes can diameters of 1500km.
Answer:
true
Explanation:
the record for the largest hurricane currently is the typhoon tip, reaching a diameter of 1,380 miles (2,220km)
Efficient production of eukaryotic proteins in E. coli may require all of the following except?
a.altered codon usage within the heterologous sequences to approximate the codon bias in E. coli
b.an E. coli expression vector with a Shine- Dalgarno sequence for efficient translation
c.a negative selectable marker to select against nonhomologous recombination events
d.The use of cDNAs as eukaryotic transgenes an E. coli expression vector with a promoter sequence that binds RNA polymerase D
(C). A negative marker to select against nonhomologous recombination events Efficient production of eukaryotic proteins in E. coli.
E. coli can it produce eukaryotic proteins?The restricted function of E. coli's eukaryotic post-translational machinery is seen as a major hindrance to the production of eukaryotic phosphoproteins, such as serine/threonine/tyrosine protein kinases.
Which proteins are produced by E. coli?The organism One of the most popular hosts for the production of recombinant proteins is Escherichia coli (Rosano and Ceccarelli, 2014). Even though E. coli's cytoplasm is where the majority of recombinant proteins are made, the periplasm is frequently where disulfide-containing recombinant proteins are made.
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Which of the following is NOT a part of adenosine diphosphate?
glucose
ribose
adenine
two phosphate groups
Answer: Glucose isn't part of ADP
Hope this helps :)
Explanation:
which of these biomes receives the least amount of rainfall, and therefore has low primary production, nutrient-poor soil, and plant species that are adapted for water storage?
Deserts receive the least amounts of rain, which results in low primary output, poor soil fertility, and native species that are specialized for water storage.
What's an example of a biome?Three types of biomes—territorial, freshwater, and marine—can be distinguished. Grasslands, deserts, and tropical woods all belong to the terrestrial biome category. Large lakes, tropical and subtropical coastal rivers, and temperate coastal rivers are examples of freshwater biomes. Polar freshwaters are another.
The most significant biome is, what?The most significant of all biomes is certainly the aquatic one. A significant natural resource is their medium, water. Numerous species spend all or a portion of their lives in water, which is the source of all life and the means by which it is sustained. Our drinking water and water for agriculture irrigation come from freshwater biomes.
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Genetic variation among humans is relatively small when compared to other species. Where in the human genome does most of the diversity occur?.
Answer:
in single nucleotide-polymorphisms
What type of cell is this
The pedigree below shows several generations of a family in which cystic fibrosis runs. A healthy phenotype is dominant (C), and cystic fibrosis is recessive (c). Shaded individuals have cystic fibrosis. Symbols with question marks have unknown genotypes and phenotypes. Individual 3 must have a genotype of:
A. CC
B. C
C. cc
D. None of the above
Answer:
Cc
Explanation:
since cystic fibrosis is present in their offspring, they must have a recessive
The presence of only one X chromosome in each body cell of a human female produces a condition known as Turner syndrome. This condition likely results from the process called
A. polyploidy
B. crossing-over
C. nondisjunction
D. hybridization
Answer:
C. nondisjunction
Explanation:
Turner syndrome likely results from the process called nondisjunction. Nondisjunction refers to the failure of chromosomes to separate correctly during meiosis, the process of cell division that occurs during the production of eggs and sperm. If nondisjunction occurs during the production of eggs, it can result in eggs with an abnormal number of chromosomes. If one of these eggs is fertilized by a sperm with a normal complement of chromosomes, the resulting embryo will have an abnormal number of chromosomes.
what is the chemical nature of matter
motor control is initiated by lower motor neurons and transmitted to upper motor neurons by interneurons situated within the cns.
Motor control is initiated by lower motor neurons and transmitted to upper motor neurons by interneurons situated within the CNS, Upper motor neurons directly contact and stimulate skeletal muscle fibers to contract.
Neurons use electrical impulses and chemical signals to transmit facts among one-of-a-kind areas of the mind and between the mind and the relaxation of the apprehensive gadget.
Neurons (also known as neurons or nerve cells) are the fundamental gadgets of the brain and fearful device, the cells liable for receiving sensory input from the outside globally, sending motor commands to our muscular tissues, and for transforming and relaying electrical alerts at every step in between.
For the spinal cord even though, we will say that there are 3 sorts of neurons: sensory, motor, and interneurons.
Sensory neurons. ...
Motor neurons. ...
Interneurons. ...
Neurons inside the mind.
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approximately what percentage of the total blood oxygen is bound to hemoglobin instead of dissolved in plasma?
One form of oxygen found in blood is dissolved in plasma and RBC water, accounting for about 2% of the total, while the other form, reversibly linked to hemoglobin, accounts for about 98% of the total.
How much oxygen is carried in plasma that is dissolved and bound to hemoglobin?Only 2% of the total oxygen carried by the blood is dissolved in the plasma directly; the majority, about 98%, is linked to hemoglobin. [6] A heme group with iron linked to a polypeptide chain makes up each of the four subunits of the metalloprotein known as hemoglobin.
How much oxygen is transported as a dissolved gas through plasma?In the blood, oxygen is delivered in two different ways: The plasma contains a minor amount of dissolved oxygen (1.5 percent). 98.5 percent of the oxygen carried by the blood is attached to the red blood cell protein hemoglobin.
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the enzymes that catalyze cellular reactions are macromolecules made of organic compounds composed of carbon, hydrogen, oxygen, and nitrogen. these types of macromolecules are known as –
Made of organic substances that contain carbon, hydrogen, oxygen, and nitrogen. These macromolecules fall under the category of proteins.
Which definition of macromolecule is the most accurate?A protein or nucleic acid is an example of a macromolecule, which is a very big molecule crucial to biophysical processes. It consists of thousands of atoms that are covalently linked. Many macromolecules are made up of smaller molecules known as monomers in polymer form.
In the body, what are macromolecules?Built from smaller organic molecules, biological macromolecules are substantial molecules required for life. Proteins, lipids, carbohydrates, and nucleic acids make up the four main groups of biological macromolecules; each is a vital part of the cell and has a variety of jobs to do.
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Write 1 paragraph summary of 'Habitat Before Conservation
Answer: a management practice that seeks to conserve, protect and restore habitats and prevent species extinction, fragmentation or reduction in range.
Explanation: Its correct :)
a glass capillary is placed into a bowl of liquid. in which scenario is the liquid in the capillary most likely to have a convex meniscus?
The cohesive forces are stronger than the adhesive forces in salad oil.
A convex meniscus takes place whilst the molecules have a stronger enchantment to each apart from the field, as with mercury and glass. A flat meniscus occurs with water in a few styles of plastic tubes constructed from fabric that water does not stick to.
In assessment, a convex meniscus curves upward in case you are looking down into the field and the meniscus curves in your direction of you. maximum drinks have concave menisci because the molecules of those beverages are more strongly attracted to the walls of their field than to each different.
Meniscus lenses are divided into wonderful and bad each is distinguished from other lenses because, by means of definition, have a convex floor and a concave floor. those lenses are often used to shorten or lengthen the focal duration of an optical system that already exists.
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80 POINTS
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please help me and i will give brainliest
Explanation:
Interphase
number of cells- two new
two new
number of chromosomes- 46 chromosomes
number of homologous- 23 pairs of homologues
After cells have finished dividing their chromosomes, and cytokinesis has divided the cell membrane, the two new cells enter the first stage of interphase,
Cytokinesis
number of cells- two daughter cells
Cytokinesis is the physical process of cell division, which divides the cytoplasm of a parental cell into two daughter cells.
Answer:.
Explanation:
.