what three categories of proteins are needed for basal transcription of protein-encoding genes in eukaryotes?

Answers

Answer 1

Three categories of proteins are needed for basal transcription of protein-encoding genes in eukaryotes are:

RNA polymerase II

general transcription factors

mediator

Depending on the gene being transcribed, one of three types of polymerases is used during transcription in eukaryotes. All of the protein-coding genes are transcribed by RNA polymerase II, whereas rRNA genes are transcribed by RNA polymerase I, and rRNA, tRNA, and short nuclear RNA genes are transcribed by RNA polymerase III. In order to start transcription in eukaryotes, a number of transcription factors must bind to intricate promoter sequences that are typically found upstream of the gene being copied. The FACT complex moves and reassembles nucleosomes as the polymerase passes by during the 5' to 3' mRNA synthesis process. Contrary to RNA polymerases I and III, which stop transcription using protein- or RNA hairpin-dependent mechanisms, RNA polymerase II continues transcription for 1,000 or more more nucleotides before cleaving the extra ones.

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Related Questions

a student observes the phenotypic traits of several hundred students at her school.which observation provides the strongest evidence that the genes encoding the two traits display genetic linkage?

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most students that have black hair also have straight hair

Hair of type 1A is very fine, straight, and devoid of any wave or curl. Because it is so straight and delicate, it tends to look oily when the natural oils reach the ends. It is the most uncommon hair kind and is typical of Asian ladies.

One of the more noticeable characteristics of human variety is hair morphology, which is especially varied among people of European heritage, where about 45% of people have straight hair, 40% have wavy hair, and 15% have curly hair.

The MC1R gene is typically present in two functional copies, one from each parent. Due to the elevated levels of eumelanin, these people have black or brown hair. More than 90% of people in the globe are thought to have dark or black hair.

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rank these events in the order in which they occur in the heart, beginning with the p wave.

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The order of the events in ECG is P wave, atrial contraction, QRS complex, ventricular contraction, t wave, ventricular relaxation.

This is an illustration of the heartbeat waves seen during an ECG. The sequence is as follows:

The first wave to be recognized, the P wave, is connected to both right and left atrial depolarization and atrial contraction.Atrial contraction (systole).The complex QRS is  The second wave, which is connected to both the right and left ventricular depolarization, appears to be visible.contraction of the ventricles.T wave – represents rapid phase 3 current when ventricular repolarization takes place.Ventricular unwind (diastole)  What is ECG?

The procedure of electrocardiography(ECG) involves creating an electrocardiogram, a recording of the electrical activity of the heart. It is a heart electrogram, which uses electrodes applied to the skin to create a graph of voltage vs time for the electrical activity of the heart.

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Complete Question:

Rank these events in the order in which they occur in the heart, beginning with the p wave.

t wave, atrial contraction, ventricular contraction, QRS complex, P wave, ventricular relaxation.

Rank from earliest to latest. To rank items as equivalent, overlap them.​

what is upwelling (biology)

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In biology, upwelling is the process by which deep, cold, nutrient-rich water rises to the surface of the ocean, often along the coastline. This occurs when the wind blows parallel to the coast and pushes the surface water away from the shore, allowing deeper water to rise to the surface.

Upwelling is an important process in the ocean because it brings nutrients from the deep ocean to the surface, where they can be used by phytoplankton and other small organisms. This, in turn, supports the growth of larger organisms such as fish, which depend on the phytoplankton as a food source. Upwelling also helps to cool the surface water and can have a significant impact on local climate and weather patterns.

FILL IN THE BLANK. fungi are multicellular decomposers that obtain nutrients by _____________.

Answers

Fungi are multicellular decomposers that obtain nutrients by extracellular digestion.

Decomposing organisms eat dead things: animal feces and leaf litter are examples of dead plant materials. As the Earth's cleanup crew, they provide a valuable service. Dead leaves, insects, and animals would accumulate everywhere without decomposers.

Food is mechanically or acidically broken down outside the cell by special molecules called enzymes during extracellular digestion. The nearby cells can then take in the nutrients that have just been broken down. When fungi eat, they use extracellular digestion. The food is broken down into components that their cells can use by their teeth, enzymes, and acid in the stomach and enzymes in the small intestine.

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Where do bacteria live?
a) anywhere
b) in volcanoes
c) in salty water
d) almost anywhere

Answers

Answer:

d) almost anywhere

Explanation:

Bacteria can live almost anywhere, including in soil, water, and even in extreme environments such as hot springs and volcanic areas.

They are found in almost every habitat on Earth. Some bacteria can even live inside other organisms, such as plants and animals.

Answer:

à) anywhere

Explanation:

bacteria is found all over ..

which portion of the coronavirus spike protein anchors the virus to the ace-2 protein binding site?

Answers

The S1 subunit of spike protein in the SARS-CoV-2 anchors the virus to the ace-2 protein binding site.

A virus named SARS-CoV-2 is responsible for the recently discovered disease known as Coronavirus disease (COVID-19). Four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins, are present in this virus. The SARS-CoV-2 spike (S) protein is made up of two subunits, S1 and S2, and is essential for receptor identification and cell membrane fusion. The host receptor angiotensin-converting enzyme 2 (ACE2) is recognized and bound by the receptor-binding domain of the S1 subunit, while the two-heptad repeat domain of the S2 subunit facilitates the fusing of the viral cell membrane. The S1 subunit associates with ACE2 to encourage the creation of endosomes, which triggers viral fusion activity in the host cell.

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FILL IN THE BLANK. generally speaking, deserts are located in places where air masses are usually ________.

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Deserts are located in the regions where the air masses are usually descending.

Deserts are the large masses of barren lands that contain sand. These areas have little to no vegetation and also do not have any huge water bodies. The precipitation is very low in such areas. About one-fifth of the Earth's land area is conquered by deserts.

Air mass can be defined as the volume of air at a significant uniform temperature, pressure and humidity. The air masses can extend for kilometers of area in any direction. The example of air masses is:  Polar, Arctic, Equatorial, Tropical, etc.

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he area around a charged object that can exert a force on other charged objects is an electric
.

Answers

Answer:

AN ELECTRIC FIELD

Explanation:

An electric field is a region around a charged object where the object's electric force is exerted on other charged objects. Electric fields get weaker the farther away they are from the charge

3. Finish the Punnett square showing two pink (RW) flowers crossed.

Answers

Answer:

results RR, RW, RW, WW

Explanation:

percentage of pink = 2/4 = 50%

percentage of white = 1/4 = 25%

percentage of red = 1/4=25%

which trait is present in apes but absent in hominins? group of answer choices mesial bridge diastema gingival space dental gap previousnext

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Great apes have a hole between the upper canines and molars to account for huge lower canines. In human advancement, teeth, jaws, and canines decreased in size, and people lost the diastema

Over numerous ages, early hominin legs developed longer and a lot further than their arms. Their feet turned out to be longer and created curves for more productive help of their bodies. Likewise, their hands turned out to be more capable of conveying and controlling items like apparatuses and food. Contrasted with present-day people, numerous hominins had toothier mouths. The "Nutcracker," (otherwise known as Paranthropus boisei), a hominin that lived 2.3 a long time back, had the biggest molars and thickest finish of any hominin. Homo erectus, which was experienced all around the world 1.5 a long time back, had bigger canines than present-day people.

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a population isolated by a geographic barrier becomes a new species as it accumulates changes by natural selection or genetic drift.target 1 of 5 2. in blank, a new species may arise as

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In allopatric speciation, a population isolated by a geographic barrier becomes a new species as it accumulates changes by natural selection or genetic drift.

Speciation is the phenomenon of formation of a new species from a group of individuals. Speciation is said to happen when the two population groups are not able to breed with each other. This reproductive isolation could be generated due to various reasons.

Genetic drift is the change in the gene frequency of a population by random chance. Genetic drift is only observed in small populations. The change in gene frequency usually results in the decrease of genes in the population.

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The enzyme dna covalently links nucleotides to synthesize new dna strands together during dna replication.

a. True
b. False

Answers

The enzyme DNA polymerase covalently links nucleotides to synthesize new DNA strands together during DNA replication. The given statement statement is true.

A particular kind of enzyme called DNA polymerase (DNAP) is in charge of creating fresh nucleic acid molecules that are copies of the original DNA. Polymers are large molecules made of smaller, repeating units that are chemically linked to one another. Nucleic acids are polymers.

As it moves along the single strand DNA template, DNA polymerase reads the nucleotide bases as it goes, adding additional complementary nucleotides to the primer to create a sequence that is complementary to the template. 749 nucleotides are thought to be replicated by DNA polymerase every second.

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Complete question :The enzyme DNA polymerase covalently links nucleotides to synthesize new DNA strands together during DNA replication.

A. True

B. False

if chlorophyll were red instead of green, making plants red in appearance, which color of light would you expect to produce the lowest rate of photosynthesis? white light blue light red light green light

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If chlorophyll were red instead of green, making plants red in appearance Because the energy is at its peak in these light ranges, the higher on the light spectrum lights, like blue and violet, indicate the fastest rate of photosynthesis in plants.

Plants use the photosynthetic pigment chlorophyll, which absorbs light rays to use during photosynthesis (synthesis of glucose).

If a plant has red chlorophyll, it will only absorb red light and not any other hues of light. Red light therefore produces the least amount of photosynthesis.

Therefore, it would be expected that the red color of light would result in the lowest rate of photosynthesis if chlorophyll were red instead of green, giving plants a red appearance.

The process of producing carbohydrates (glucose) through photosynthesis uses sunlight that is captured by the chlorophyll pigment found in plant cells.

The primary photosynthetic pigment in plants, chlorophyll, absorbs light photons to carry out photosynthesis.

Any other colors of light besides red will not be absorbed by a plant if its chlorophyll is red. This indicates that plants will produce the least amount of photosynthesis when exposed to red light.

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FILL IN THE BLANK. if a rational function is proper, then _______ is a horizontal asymptote.

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if a rational function is proper, then y=0 is a horizontal asymptote.

A rational function's horizontal asymptote can be found by examining the degrees of the numerator and denominator. If N is the numerator's degree and D is the denominator's degree, and N D, then the horizontal asymptote is y = 0. Divide the numerator by the denominator to obtain the asymptote. The equation for the slant asymptote is the quotient.

A horizontal asymptote is a parallel line to which a portion of the curve is very close. However, a HA should never contact any section of the curve (but it may cross the curve). Example: Determine the horizontal asymptote of the function f(x) = 2x / 2. (x - 3). So y = 2 is the HA of the function.

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what changes occur in height, weight, and body composition with aging? what accounts for these changes? how do these changes affect maximal oxygen uptake?

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The changes that occur in height, weight and body composition with aging are loss of bone density, weaker muscles, decrease in height and weight can vary according to the diet intake by the body.

It is believed that reduction in height growth stops at the age of 20 for most of the people but studies how that height continue to increase till the age of 35-40 years but then it stops because of compression of the intervertebral disk. Osteopenia is the reduction in bone mineral density and osteoporosis refers to severe loss of bone mass with deterioration of the microarchitecture of bone. It causes increased chances of fracture. It also has hormonal links in adults along with poor diet and low exercise. Weight gain is common during pregnancy (in women) and excess caloric intake, and inability to mobilize fat stores but as age increases, weight decreases as body loses bone calcium and muscle mass. Exercise training can help to alter these process or slow the deterioration rate to some extent. It will also enhance oxygen uptake by the body.

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what type of transport is needed to move molecules of the substance from outside the cell to inside

Answers

active transport would be the correct answer:)

all dna polymerases require a primer with a 3’ oh group to begin dna synthesis. the primer is:

Answers

All DNA polymerases require a primer with a 3’ oh group to begin dna synthesis. The primer is a short stretch of RNA nucleotides.

DNA polymerases are characterised by their inability to manufacture new DNA strands from scratch, i.e., without first polymerizing 2 dNTPs. Instead, DNA is synthesised by DNA polymerases that need a stable primer that is already attached to the template strand. Primers are needed because DNA polymerases, which add deoxyribonucleotides to a fresh DNA strand, can only do so to the 3'-OH group of the an existing chain and cannot start synthesis from scratch.

Without an existing 3′-OH, DNA polymerase cannot create new DNA. As a result, an RNA primer is needed for DNA replication to begin before strand creation. While RNA polymerase is utilised during transcription to create the mRNA strand, DNA polymerase creates a DNA strand and is employed in DNA replication. Contrary to DNA polymerase, RNA polymerases need not truly have proofreading mechanisms and do not always require the so-called primer to begin the activity.

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M protein, hyaluronidase, collagenase, and often a capsule, can be virulence factors for certain pathogenic strains of:

a.Mycobacterium
b.Streptococcus
c.Neisseria
d.Staphylococcus
e.Yersinia

Answers

M protein, hyaluronidase, collagenase, and often a capsule, can be virulence factors for certain pathogenic strains of Streptococcus. Correct answer: letter B.

This is because they allow bacteria to adhere to and penetrate the host's tissues, as well as help evade the host's immune response. While hyaluronidase, collagenase and capsule are components of the bacterial cell wall.

What is streptococcus bacteria?

Streptococcus is a genus of bacteria that includes several species commonly found in the human body. These bacteria are spherical or ovoid in shape, and typically grow in chains or pairs. Many species of Streptococcus cause diseases in humans, including:

Strep throatPneumoniaMeningitisEar infections

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1. Which of the following hormone is expected to increase in the body after consuming a banana split?
(a) Growth hormone
(b) Testosterone
(c) Insulin
(d) Thyroid hormone

Answers

Answer is c) insulin

Explanation- after eating a banana split the blood sugar level rises and the pancreas produces insulin, which is a hormone that starts cells to absorb blood sugar for energy or stores it

superantigen type toxins lead to the release of excessive amounts of __________________ stimulating a hyperactive immune response that can lead to shock and death in the affected individual.

Answers

Superantigen type toxins lead to the release of excessive amounts of cytokines stimulating a hyperactive immune response that can lead to shock and death in the affected individual.

In the field of biology, such a kind of antigen that is responsible for the production of an excessive immune response is referred to as a superantigen.

As a result of superantigen-type toxins invading the body, more cytokines will be produced. This is because cytokines are sites of the body that are involved in the production of immune cells. Ahyperactivates immune response can be shocking for the body and the brain might pass a message to kill its own immune cells. Hence, this can lead to the death of an individual.

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why might the cricket genome have eleven times as many base pairs as that of drosophila melanogaster?

Answers

There must be more non-coding DNA in crickets. The genome of the cricket may contain 11 times more base pairs than the genome of the Drosophila melanogaster.

What is DNA and what does it do?

DNA is the molecule of information. It provides the knowledge required to produce proteins, another type of substantial molecule. Each of your cells contains 46 substantial structures genetic code that are distributed throughout these instructions. These chromosomes are made up of numerous smaller segments of DNA, called genes.

What are the three main goals of the DNA?

Nowadays, DNA has three distinct functions: genetic, immune, and functional, all of which are significantly different between each other and rely on the letters and the sugar - phosphate backbone backbone in different ways. Ribonucleotide reductases in modern cells break down ribonucleotides di- or tri to produce DNA precursors.

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How are meiosis and mitosis different?

A. Only mitosis produces haploid cells from diploid cells.

B. Mitosis has two rounds of nuclear division, but meiosis has only one.

C. Meiosis results in four cells, but mitosis results in two cells.

D. Chromatids form only during the process of meiosis.​

Answers

Answer:

C. Meiosis results in four cells, but mitosis results in two cells.

Explanation:

Mitosis is a process where a single cell divides into two identical daughter cells (cell division), whereas meiosis is a process where a single cell divides twice to produce four cells containing half the original amount of genetic information.

Structure A refers to the _____.
chromarid
centromere
chromosome

Answers

CHROMOSOMEStructure A refers to the chromosome.Structure B refers to the centeomere.Structure C refers to the chromatid.

if dna is damaged or incompletely replicated in s phase, the inhibition of which of these molecules prevents the cell from entering m phase?
a. Cdc6
b. Cdc25
c. S-Cdk
d.ORC

Answers

Answer:

CDK

Explanation:

If DNA is damaged or incompletely replicated in S phase, the inhibition of cyclin-dependent kinase (CDK) prevents the cell from entering M phase.

During S phase, the DNA of a cell is replicated in preparation for cell division. If this replication is incomplete or if the DNA is damaged, it can lead to problems with the cell's ability to divide properly. In such cases, the cell will not be able to enter M phase, which is the phase of the cell cycle in which the cell divides into two daughter cells.

One of the key molecules that controls the transition from S phase to M phase is cyclin-dependent kinase (CDK). CDK is an enzyme that plays a critical role in the regulation of the cell cycle. It is activated by a protein called cyclin, which is produced during S phase.

When DNA is damaged or incompletely replicated in S phase, the levels of cyclin are likely to be reduced. This, in turn, can lead to the inhibition of CDK, preventing the cell from entering M phase. As a result, the cell will not be able to divide properly, and this can have serious consequences for the health of the organism.

In summary, if DNA is damaged or incompletely replicated in S phase, the inhibition of CDK can prevent the cell from entering M phase. This helps to protect the organism from the potential harmful effects of damaged or incompletely replicated DNA.

how is a true breeding yellow-seeded pea plant different from a hybrid yellow-seeded pea plant?

Answers

A hybrid yellow-seeded pea plant possesses genotype (Aa) - one dominant, one recessive allele, whereas true-breeding yellow-seeded pea plants have (AA) - both dominant alleles.

Even though they have the same phenotypic, true breeding yellow-seeded pea plants differ from hybrid yellow-seeded pea plants because their genotypes are different.

They have the same genotype but different phenotypes, the same phenotype but different genotypes, the same genotype and phenotype, and they have a different genotype and phenotype.

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these heterozygous parents having the genotype ttyy will produce how many gametes and what are the genotypes of these gametes?

Answers

Since genotype TtYy is heterozygous for two genes i.e. it has both dominant and recessive alleles of two genes, it will form total four types of gametes.

The presence of two different alleles at a particular gene locus. A heterozygous genotype may include one normal allele and one mutated allele or two different mutated alleles (compound heterozygote).

People with genotypes AA and aa are homozygotes, which means they have two copies of the same allele. Individuals with genotype Aa have two different alleles at the A locus, i.e., they have two different alleles at the A locus.

You have a heterozygous genotype for that gene if the two versions differ. Being heterozygous for hair color, for example, means you have one allele for red hair and one allele for brown hair. The interaction of the two alleles influences which traits are expressed.

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what are the functions of simple sugars

Answers

Answer:  produce a spike in blood glucose, providing the body with a short-lasting source of energy.

Explanation:

describe the genetic mutations that you think occurred in the cancer cells that were responsible for the phenotypic differences between the healthy and cancer cells you observed.

Answers

Genetic mutations are changes in the genetic material of a cell that can cause alterations to its phenotype. The phenotypic differences between healthy and cancer cells can be attributed to a number of different types of genetic mutations that can occur in the cells.

The most common type of genetic mutation associated with cancer cells is the somatic mutation. This occurs when a single gene in the cell is mutated, leading to changes in the cell’s structure and function. Somatic mutations can lead to changes in the proteins produced by a cell, which can cause changes in the cell’s ability to divide, survive, or differentiate. These changes can lead to uncontrolled cell division, which is a major trait of cancer cells.

Another type of genetic mutation associated with cancer cells is chromosomal abnormalities. These occur when pieces of chromosomes are either missing or rearranged. Chromosomal abnormalities can lead to changes in the proteins produced by a cell, as well as changes in the expression of other genes. These changes can also lead to uncontrolled cell division, making them a common feature of cancer cells.

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the part of a bacterial cloning vector that contains many restriction enzyme recognition sequences is called a...

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The part of a bacterial cloning vector that contains many restriction enzyme recognition sequences is called  Multiple cloning site.

In biotechnology, bioengineering, and molecular genetics, multiple cloning sites are a feature that allows for the insertion of foreign DNA without damaging the rest of the plasmid. Using genetic engineering, MCS can help create transgenic organisms, also known as genetically modified organisms (GMOs). When the MCS is cut open during manufacture, a gene of interest must be introduced to the vector in order to use the MCS for genetic engineering. The gene of interest will be present in the MCS after it has been created and ligated, and it can be amplified to increase the number of copies of the gene in a bacterial host. The gene of interest can be removed from the bacteria after it has replicated.

In some cases, a protein product can be made using an expression vector. Once the products are identified, they can be used for a wide range of purposes, including the manufacturing of insulin, vaccines, antibiotics, and gene treatments.

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the mycelial growth habit leads to a body with a high surface-area-to-volume ratio.

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Mycelia have a large surface area for absorption.

Mycelium is a fungus root-like structure made up of branching, thread-like hyphae. Mycelium-based fungal colonies can be found in and on soil as well as many other substrates. Mycelia play an important role in the breakdown of plant material in terrestrial and aquatic habitats. They contribute to the organic part of soil, and their growth releases carbon dioxide back into the atmosphere.

Mycelium can be unappealing since it might appear as white fuzz that resembles mould. While we would never advocate eating anything mouldy or mushrooms without first confirming that they are suitable for human nutrition, most mycelium is safe to consume and completely edible.

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A 4.0 kg bucket of water is raised from a well by a rope.The acceleration of gravity is 9.81 m/s2 .If the upward acceleration of the bucket is 2.6 m/s2, find the force exerted by the rope on the bucket of water.Answer in units of N A steep line has a bigger ____________ than a flat line All of the following are TRUE statements regarding the requirements of an insurer to offer earth movement coverage in California EXCEPTA Only authorized agents which hold an "earth movement certificate" through the department of insurance are able to market residential property insurance which provides coverage for earth movement.B No policy of residential property insurance may be issued or delivered or initially renewed in this state by any insurer unless the named insured is offered coverage for loss or damage caused by the peril of earthquake.C Coverage may be provided in the policy of residential property insurance which specifically provides coverage for loss or damage caused only by the peril of earthquake by itself.D Coverage may be provided in the policy of residential property insurance which specifically provides coverage for loss or damage caused by the peril of earthquake alone or in combination with other perils.A Only authorized agents which hold an "earth movement certificate" through the department of insurance are able to market residential property insurance which provides coverage for earth movement.correct! No additional certificate is required to market earth movement coverage. genent industries, inc. (gii), developed standard costs for direct material and direct labor. in 2015, gii estimated the following standard costs for one of their major products, the 30-gallon heavy-duty plastic container. budgeted quantity budgeted price direct materials 0.30 pounds $20 per pound direct labor 0.20 hours $12 per hour during july, gii produced and sold 3,000 containers using 1,100 pounds of direct materials at an average cost per pound of $19 and 625 direct manufacturing labor hours at an average wage of $11.75 per hour. the direct material price variance during july is . 16.13- cerebral tumors and cell phone use. in a case-controlled study on cerebral tumors and cell phone use, tumors occurred more frequently on the same side of the head where cellular telephones had been used in 26 of 41 cases. test the hypothesis that there is an equal distribution of contralaterial and ipsilateral tumors in the population. use a two-sided alternative. green and yellow dye are mixed in a 5:6 ratio to make 44 litres of lime-coloured dye. 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Which of the following statements is best supported by the images?Image 2 shows an innovation that occurred in the Second Agricultural Revolution, reducing the amount of labor needed and increasing crop yields,DImage 2 shows an innovation that occurred late in the First Agricultural Revolution, increasing farmers' profits.CImage 1 shows an innovation that occurred early in the Second Agricultural Revolution resulting in more sustainable livestock production,DImage 2 shows an innovation that occurred in the Third Agricultural Revolution, resulting in a diffusion of agricultural practices to less developed countries.Image 1 shows an innovation that occurred early in the Third Agricultural Revolution, improving the standard of living for small farmer families. The amortization of the bond discount the carrying value of the bond, while the amortization of the bond premium the carrying value of the bond.a) decreases, increasesb) increases, decreasesc) increases, increasesd) decreases, decreases An open-market purchase of government bonds accompanied by a decrease in income taxes will result in which of the following in the short run?A decrease in real outputA decrease in the price levelA decrease in nominal wagesA decrease in unemployment when more than one gene controls a trait and the result is often a continuum (gradient) of phenotypes rather only two distinctive options this is called what? if there is a facially neutral policy that unintentionally discriminates against a group of individuals, this type of discrimination is known as . a client who is taking estrogen therapy calls the clinic and tells the nurse that she is experiencing sudden, sharp chest pain. the nurse suspects the client is experiencing what adverse reaction related to estrogen therapy? the brilliant french satirist who wrote against inequality, injustice, and supserstittion, detested the slave trade, and deplored religious prejudice was... Lithium has two isotopes with mass number 6 and 7. If the relative atomic mass oflithium is 6.94, determine the percentage abundance of each isotope. which of the following are similarities between film and digital movie making, and which are differences? Question of the picture is below An accountant performing a nonissuer's review engagement is considering the appropriateness of a client's balance for accrued wages. The accountant should perform each of the following procedures, except:A. Testing the process used by management to determine the balance.B. Comparing the current-year balance to the prior-year balance.C. Obtaining representations from management regarding the year-end balance.D. Making inquiries of the payroll accountant regarding completeness of the account balance. x^2-12x+43 i need some help with this maths question Your goal here is to find the least squares line y(x) = mx + b for the following data: (-2, 1), (2, 1), (-1,-1), (0, -2), (2,-2), and (-2, 1) Feel free to use a calculator! The normal equation for determining the approximating parameters and n are: Then the least squares line is: y(x) = = number + number