The DNA determines the RNA, and the RNA determines the protein, and the protein
determines the ?

Answers

Answer 1

Answer: Section 4.4The Three Roles of RNA in Protein Synthesis. Although DNA stores the information for protein synthesis and RNA carries out the instructions encoded in DNA, most biological activities are carried out by proteins. brainliest?

Explanation:


Related Questions

Explain how growers might intervene in the plant's life cycle to solve these problems??

Answers

There are many pesticides on the market that have been created to control plant diseases by either stopping the pathogens' growth or by killing them.

What are pathogens?

Pathogens are defined as an organism that infects its host, whose virulence is determined by how severe the disease symptoms are. Pathogens include viruses, bacteria, unicellular and multicellular eukaryotes, as well as other taxonomically diverse organisms.

Cultural methods include sanitation, removing infected plants or plant parts, rotating crops, removing weeds or other plants that can be secondary hosts for the disease, and discouraging or preventing insect vectors are all part of reducing the amount of infection.

Thus, there are many pesticides on the market that have been created to control plant diseases by either stopping the pathogens' growth or by killing them.

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TRUE/FALSE. if the concentration of hydrogen ions (h ) outside of the thylakoids were equal to the concentration of h inside the thylakoids, how would it affect the chloroplasts? (4 points) the chloroplasts would release excess o2. the chloroplasts would be unable to generate atp. the chloroplasts would make more glucose molecules. the chloroplasts would make more nadph than usual.

Answers

Answer:

False. The chloroplasts would be unable to generate ATP.

Red flowers (R) are dominant to white flowers (r). Parent 1 has white flowers. Parent 2 is heterozygous.

Answers

Answer: Rr X rr

Rr Rr rr rr

Explanation:

What are the 2 steps of the mitotic phase?
Summarize how often cells divide:
Explore: Cell Division (p.5)
What does the cell do when not in the mitotic phase?

Explore: Cell Division (p.7)
__________ in animal cells involves the pinching of the cell's __________ until the two newly formed cells separate.

Explore: Cell Division (p.8)
Cytokinesis in __________ cells involves the building of a new cell __________ and cell membranes between the two newly formed nuclei.

Answers

Fleming divided mitosis into two broad parts: a progressive phase, during which the chromosomes condensed and aligned at the center of the spindle, and a regressive phase, during which the sister chromatids separated.

Happy Holidays!!

What is the action of the Scalenes?

Answers

to elevate the first rib, as well as flexes and bends the neck

the law of states that genes have alternative forms, or alleles. in a organism, the two alleles of a gene separate during and gamete formation; each sperm or egg carries only one allele of each pair. this law explains the ratio of the f2 phenotypes observed when self-pollinate. each organism inherits one allele for each gene from each parent. in individuals, the two alleles are different, and expression of the allele masks the phenotypic effect of the allele. in individuals, the two alleles are identical.target 1 of 12 target 2 of 12 target 3 of 12target 4 of 12target 5 of 12target 6 of 12target 7 of 12target 8 of 12target 9 of 12 the law of states that the pair of alleles for a given gene segregates into gametes independently of the pair of alleles for any other gene. this law explains the ratio of the f2 phenotypes in a cross between .

Answers

The law of Segregation states that genes have alternative forms, or alleles. In an organism, the two alleles of a gene separate during and gamete formation; each sperm or egg carries only one allele of each pair. this law explains the ratio of the f2 phenotypes observed  monohybrids self-pollinate.

Each organism inherits one allele for each gene from each parent. In heterozygotes, the two alleles are different: expression of the dominant allele masks the phenotypic effect of the recessive allele. Homozygotes have identical alleles of a given gene and are true-breeding.

The law of independent assortment states that the pair of alleles for a given gene segregates into gametes independently of the pair of alleles for any other gene. In a cross between dihybrids (individuals heterozygous for two genes), the offspring have four phenotypes in a 9:3:3:1 ratio.

What are phenotypes?

The phenotype is described as the set of observable characteristics or traits of an organism which covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior.

In conclusion, Gregor Mendel formulated a theory of inheritance based on experiments with garden peas. During the experiment, he proposed that parents pass on to their offspring discrete genes that retain their identity through generations. This theory includes two “laws that was described above.

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Practice: Photosynthesis and Cellular Respiration Comparison
Fill in the chart below, showing the similarities and differences between these two processes.

Answers

the process by which organism combine oxygen with food molecules diverting the chemical energy in this substance into life sustaining activities discarding

of waste product carbon dioxide water

Explanation:

photosynthesis is a process which is used for plants and other organisms convert light energy into chemical energy that in to through cellular respiration

What does a community contain that a population does not?
OA. Abiotic factors
OB. Multiple organisms
OC. Biotic factors
OD. Multiple species
TRUNS
MATER
UNMING
TREENUE
(2000)

Answers

Answer: all various sorts of organisms, including microbes, fungi, animals, and plants.

Explanation:

which of the following statements provides the most reasonable prediction to account for the deviation from the expected results?

Answers

In sweet pea plants, the gene for flower color and the gene for pollen grain shape are genetically linked.

What is gene?

Qualities are the essential physical and useful units of heredity. Qualities are made of DNA. A few qualities go about as directions for making particles called proteins. Be that as it may, numerous qualities don't code for proteins. In people, qualities differ in size from a couple hundred DNA bases to north of 2,000,000 bases. A worldwide examination project called the Human Genome Undertaking attempted to arrangement the human genome and recognize the qualities it contains.

Everybody has two duplicates of every quality, each parent acquired individually from Most qualities are a similar in everybody, except a couple of qualities (under 1% of her generally speaking) are marginally not the same as one individual to another. Alleles are types of similar quality with slight contrasts in the arrangement of DNA bases. These little distinctions add to every individual's interesting actual qualities.

In sweet pea plants, the quality for blossom tone and the quality for dust grain shape are hereditarily connected.

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the images represent ecosystems in the eastern united states. rank the ecosystems by their ability to remove and store carbon, from greatest to least.

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The mangrove forest which holds the most Carbon dioxide followed by forest shown by second image and at last the vegetation on farms holds and releases the least amount of Carbon dioxide.

Carbon is transferred through one storage reservoir to another through a range of mechanisms. Plants, for example, transfer carbon dioxide from the atmosphere into the biome via photosynthesis in the food chain. They use solar energy to chemically incorporate carbon dioxide, hydrogen, and oxygen from water to form sugar molecules. Animals that consume plants metabolize the sugar molecules to obtain energy. Respiration, excretion, and decomposition all return carbon to the atmosphere or soil, thus completing the cycle.

Erosion, for example, releases carbon into the atmosphere slowly, whereas volcanic activity releases it quickly. Another way to quickly release carbon into the atmosphere is to burn fossil fuels in automobiles or power plants.

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Two bird species that originally ate the same insect species but that eventually evolve to eat different insect species to reduce competition are demonstrating ____.

Answers

Two bird species that originally ate the same insect species but that eventually evolve to eat different insect species to reduce competition are demonstrating Resource partitioning.

Resource partitioning is the process of dividing up resources within an ecosystem to prevent species from competing for scarce resources. It's an evolutionary change that makes it easier for different species to live together in an ecological community.

A food resource may be consumed in different ways by various species. The other insect might be eaten by one species. As a result, various species coexist and can meet their needs with the limited resources available. A few animal categories are dynamic during the daytime and some are more dynamic during the evening. Subsequently, resource partitioning helps in the concurrence of various species.

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Evidence indicates that plants increase the number of stomata in their leaves as atmospheric CO2 levels decline. Increasing the number of stomata per unit surface area should have the effect of doing which of the following?
1. increasing dehydration of leaf tissues 2. decreasing dehydration of leaf tissues 3. countering the effect of declining CO2 on photosynthesis 4. reinforcing the effect of declining CO2 on photosynthesis 5. decreasing the O2 content of air next to the leaves lower than it would otherwise be 6. increasing the O2 content of air next to the leaves higher than it would otherwise be

Answers

The increase in the number of stomata per unit surface area may lead to increased dehydration of leaf tissues, Countering the effect of declining Carbon dioxide on photosynthesis and increasing the Oxygen content of air next to the leaves higher than it would otherwise be.

Leaf stomata are where the exchange of gases takes place in the gas. The CO2 required for photosynthesis enters through stomata, and the byproduct O2 is released through stomata. The temperature regulation of the leaf is done by transpiration. Water evaporation takes place and the overall temperature of the leaf is reduced which helps in protecting cytochromes, pigments, and membranes.

The number of stomata per unit area, the size of the stomata, and the speed of opening and closing of stomata determine the gas exchange through the leaf. So as there is an increase in stomata per unit area, the Carbon dioxide intake is increase, the transpiration rate increases, and more oxygen gets released to the surroundings.

So as the number of stomata per unit surface area increases, the gas exchange and transpiration rates increase.

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determine the results from a cross of a mother and a father who are both heterozygous for freckles. (some labels may not be used.)

Answers

Answer:

Uh so x=freckles and there are 26 letters in the alphabet the z is the last what else is last a rotten egg whose the rotten egg not me its the down bad mother and father that want freckles so the result of your wander is Andrew tate

Explanation:

its about drive

I NEED HELP!!! If bacterial cells which can do both anaerobic and aerobic respiration are put in separate containers of oxygen and no oxygen which container would have bacteria that made more ATP?

Answers

Answer:  containers with oxygen

Explanation:


It is likely that the bacteria in the container with oxygen would produce more ATP through aerobic respiration than the bacteria in the container without oxygen, which would have to rely on anaerobic respiration to produce ATP. This is because aerobic respiration is generally more efficient at producing ATP than anaerobic respiration. However, it is important to note that the specific amount of ATP produced by the bacteria in each container would depend on a variety of factors, such as the type of bacteria and the availability of other nutrients.

___data includes descriptions observations and explanations

Answers

Answer:

Scientific data includes descriptions, observations, and explanations.

Explanation:

Descriptions in scientific data refer to the characteristics or properties of the objects or phenomena being studied. They may include measurements, such as size, shape, or mass, or other characteristics, such as color, texture, or behavior.

Observations in scientific data are the results of collecting and analyzing data using scientific methods. They may include measurements, counts, or other data that has been collected through experiments, observations, or other methods.

Explanations in scientific data are the interpretations or explanations of the observations and data that have been collected. They may involve proposing hypotheses or theories to explain the data, or making predictions about future observations or experiments.

Overall, scientific data includes a variety of different types of information, including descriptions, observations, and explanations, that are used to understand and explain the natural world.

Descriptions in scientific data refer to the characteristics or properties of the objects or phenomena being studied.

What is Scientific description?

They may include measurements, such as size, shape, or mass, or other characteristics, such as color, texture, or behavior.

Observations in scientific data are the results of collecting and analyzing data using scientific methods. They may include measurements, counts, or other data that has been collected through experiments, observations, or other methods.

Explanations in scientific data are the interpretations or explanations of the observations and data that have been collected. They may involve proposing hypotheses or theories to explain the data, or making predictions about future observations or experiments.

Therefore, Descriptions in scientific data refer to the characteristics or properties of the objects or phenomena being studied.

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TRUE/FALSE. heritability is a measure of the degree to which the phenotypic variation of a giden trait is due to genetic factors

Answers

It is true that heritability is a measure of the degree to which the phenotypic variation of a given trait is due to genetic factors.

In the fields of breeding and genetics, a statistic known as heritability is used to estimate the amount of variation in a phenotypic trait that is caused by genetic variation between individuals in a population.

Intelligence, height, and eye color are examples of traits, as are disorders like schizophrenia and autism spectrum disorder.

Estimates of heritability range from 0 to 1. A heritability near zero shows that practically all of the fluctuation in a characteristic among individuals is because of ecological elements, with very little impact from hereditary contrasts.

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Fears of radiation exposure from normal use of such detectors are largely unfounded. Identify reasons why 241Am smoke detectors are perfectly safe.
Choose all that apply.
A Ions get trapped by electrodes.
B The detector has a plastic cover.
C The detector is housed in an aluminum case.
D The amount of americium is very little.
E The penetrating power of α radiation is limited.
F The number of α particles leaving the case is low

Answers

The reasons why  241am smoke detectors are perfectly safe is because;

(i)   The amount of americium is very little.

(ii)   The aluminum core is where the detector is hosted.

(iii)  The detector has a plastic cover.

(iv)   Radiation is limited in penetrating power.

(v)   There is a low number which is leaving the case.

(iv)  Ions get trapped by electrodes.

What is 241 Am smoke detectors?

Because it detects a wide variety of fire situations, Americium 241 is utilized in smoke detectors. They are also less costly and simpler to install than photoelectric lights.

Americium emits an alpha - particle with a 0.9 micro-Curie value. In the detector's ionization chamber, these alpha particles hit with oxygen and nitrogen in the air to produce charged particles, or ions.

A low level voltage placed across the chamber collects these ions. A modest continuous electric current runs between two electrodes when the ions are collected.

If smoke reaches the detector, smoke particles will bind to the ions generated by the alpha particles and oxygen or nitrogen. As fewer ions arrive at their target, the electric current decreases, triggering the alarm.

Hence, the use of 241am smoke detector

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identify 1 thing that you could reasonably and personally commit to doing that could reduce your carbon footprint.

Answers

If the first cause in a series of effective causes were to disappear, the subsequent causes would be rendered impossible.

1. Which of the following conditions does not lead to a change in gene expression patterns in bacteria cells? A. Sporulation B.Heat shock C.Nutrient availability D.Nitrogen deprivation E.None of the choices are correct

Answers

Sporulation conditions do not lead to a change in gene expression patterns in bacteria cells.

Sporulation is a strategy used by a wide range of organisms to respond to shifts in their personal environmental subcultures and sustain in time and/or space until conditions suitable for vegetative growth are met. Sporulation is primarily triggered by nutrient deficiency; however, this process necessitates the expenditure of energy. Sporulation creates a multilayered framework that can be sustained for an extended period of time.

Gene expression refers to the procedure by which a gene's information is utilized in the formation of a fully functioning gene product, allowing it to generate end products such as protein or non-coding RNA and, as a result, affect a phenotype. The method by which a gene in a cell is activated to produce RNA and proteins.

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HELP ME! Some organisms like squirrels will give a warning call if a predator is near. Why do squirrels do this if they threaten their own existence?

Answers

In order to defend themselves and their homes, squirrels make noise and give a warning call if a predator is near.

Why do squirrels make sound if a predator is near?

The squirrel will begin producing warning sounds when the predator is close by and moving toward its territory. It is said that they sound like a sequence of barking calls. These noises may be a buzz, which sounds more like a fast sound coming from the nose. They produce screeches, rattles, barks, or snorts as their alarm calls. These noises are quite faint and hardly audible.

By doing this, the odds of the group surviving can be increased, and danger can be avoided. While alarming the group could put one squirrel in danger, there are benefits to doing so as well.

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spectra occur when objects stand in the path of the
objects you intend to view and remove certain wavelengths of
light you expect from your sample.

Answers

Yes, spectra occur when objects stand in the path of the objects you intend to view and remove certain wavelengths of light you expect from your sample

What is spectra?

An illustration of the intensity of light being emitted over a variety of energies is known as a spectrum.

Since the lines depict the wavelengths that are emitted from atoms when electrons transition from one energy level to another, line spectra are also known as atomic spectra.A spectrum is a state that can fluctuate without gaps along a continuum and is not constrained to a single set of values. After passing through a prism, visible light takes on a rainbow of hues, which is how the term was initially used scientifically in optics.

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In our current day, one of the antibiotics used to treat typhoid fever is azithromycin. azithromycin works by binding to the large (50s) ribosomal subunit, inhibiting translation in s. typhi. this mode of action is most similar to which of the following antibiotics?
- Tetracycline
- Quinolones
- Sulfa drugs
- Penicilin
- Vancomycin

Answers

Azithromycin inhibits translation in S. Typhi by binding to the large (50S) ribosomal subunit. This mechanism of action is most similar to that of Sulfa drugs.

Sulfa drugs work by binding to and preventing a specific enzyme known as dihydropteroate synthase (DHPS). This enzyme is essential for the synthesis of folate, a nutrient. Mammals get their folate from their diet, but bacteria must synthesize it.

Sulfonamides, also known as "sulfa drugs," are a class of antibiotics that treat bacterial infections.

Sulfa drug, also known as sulfonamide, any of a class of synthetic antibiotics with the sulfanilamide molecular structure. Sulfa drugs were among the first chemical compounds that were used systematically to prevent and treat bacterial infections in humans.

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if a mutation is made within the active site of an enzyme resulting in a decrease in km, which of the following will be true with respect to the enzyme kinetics? The Vmax of the reaction will increase
The concentration of substrate needed to reach ½ Vmax will not change
The enzyme will require a higher substrate concentration to reach ½ Vmax
The enzyme will require a lower substrate concentration to reach ½Vmax

Answers

A mutation is made within the active site of an enzyme resulting in a decrease in km, which of the following will be true with respect to the enzyme kinetics. The Vmax of the reaction will increase when the enzyme will require a lower substrate concentration to reach 1/2 Vmax.

A mutation might or might not have an effect on an organism's phenotype, or its outward features. Evolution, cancer, and the maturation of the immune system, including junctional variation, are among the beneficial and ill biological processes in which mutations take part. All genetic variety results through mutation, which also provides the justification for the action of forces of evolution like natural selection.

The complete question is:

If a mutation is made within the active site of an enzyme resulting in a decrease in Km, which of the following will be true with respect to the enzyme kinetics?

a) The concentration of substrate needed to reach 1/2 Vmax will not change

b) The enzyme will require a higher substrate concentration to reach 1/2 Vmax

c) The enzyme will require a lower substrate concentration to reach 1/2 Vmax

d) The Vmax of the reaction will increase

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PLEASE HELP BY TONIGHT: The ability to taste phenylthiocarbamide (PTC) is controlled in humans by a single dominant allele (T). A woman who is a nontaster married a man and they had three children, two boy tasters and a girl nontaster. All the grandparents were tasters. Create a pedigree of this family of this trait. Solid symbols should signify nontasters. Where possible, indicate whether the tasters are TT or Tt.

Answers

Here is a possible pedigree for this family:

T
/ \
T T
/ / \
T T t
/ / /
T T t

In this pedigree, the woman who is a nontaster is represented by a solid circle, and the man is represented by an open circle. The two boy tasters are represented by open squares, and the girl nontaster is represented by a solid square. The grandparents are represented by open triangles.

In this pedigree, the man and both of his parents are tasters, so they are likely to be TT genotypes. The woman and her parents are nontasters, so they are likely to have a genotype of tt. The two boy tasters are likely to have a genotype of Tt, and the girl nontaster is likely to have a genotype of tt.

which of the following occurs in both aerobic and anaerobic respiration? group of answer choices krebs cycle calvin cycle glycolysis electron transport chain

Answers

The procedure familiar in both aerobic and anaerobic respiration is Glycolysis and is oxygen independent.

Glycolysis takes place in the cytoplasm. In this process glucose breaks down to form pyruvate, a three carbon molecule.

Glycolysis is a routine step for both aerobic and anaerobic respiration. It takes place in the cytoplasm and is independant of the presence or absence of oxygen. Two molecules of pyruvic acid/ pyruvate is formed as the end product of glycolysis.

In aerobic conditions, pyruvate enters the citric acid cycle and undergoes oxidative phosphorylation leading to the net product of 32 ATP molecules. In anaerobic conditions, pyruvate converts to lactate through anaerobic glycolysis.

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e. coli bacteria are placed into a medium containing both glucose and lactose. which of the gene products (i.e., enzymes) listed below do you predict will be fully transcribed?

Answers

E) None of the possible solutions is accurate. E. coli organisms are added to a medium that contains both lactose and glucose.

Lactose can be broken down more slowly and with less energy than glucose. However, if lactose is the only sugar present, E. coli will immediately start using it as fuel. The lac operon genes, which encode vital enzymes for lactose absorption and processing, must be expressed for the bacteria to utilise lactose.

Since glucose is the preferred carbon source for E. coli cells, adding glucose to the medium will stop them from absorbing lactose. As a result, the lac-operon will be suppressed in these bacterial cells. B.

Lactose binds to the repressor and stops it from binding to the operator region if both glucose and lactose are present. As a result, the restriction on lac gene transcription is removed, and some mRNA is generated.

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Question :-

E. coli bacteria are placed into a medium containing both glucose and lactose. Which of the gene products (i.e., enzymes) listed below do you predict will be "turned on"?

A) -galactosidase

B) lacI

C) lacP

D) permease

E) None of the answer options are correct.

This is a microscopic image of an animal tissue.

Which type of animal tissue is shown in the image?
OA. Epithelial tissue
B. Muscular tissue
C. Nervous tissue
O D. Connective tissues

Answers

Answer:

A) Epithelial Tissue

Explanation:

Epithelial tissue is made up of layers of tightly packed cells that line the surfaces of the body for protection, secretion, and absorption. Examples of epithelial tissue include the skin, the lining of the mouth and nose, and the lining of the digestive system.

the middletown park is located next to a school. the park is mostly grass with a few trees. some students noticed that sometimes there are a lot of grasshoppers in the park, and sometimes there are very few. they were interested in what could be limiting the grasshopper population. the students began a year-long study. they collected data on the populations of grass, grasshoppers, and purple martins (a type of bird).

Answers

according to the quantity of grasshopper eggs, grasshopper populations Predators such as birds and spiders can typically reduce grasshopper populations if the spring egg production is modest.

Predators like birds and spiders can typically keep grasshopper populations in check if egg quantities are low in the spring. However, when eggs are very plentiful in the spring, more grasshoppers hatch and predators are unable to manage the populations, which can indicate serious issues for rangeland ecosystems. The immature grasshoppers might actually compete for the rarer, highly nutritious food plants if there are a lot of grasshoppers around, starving to death before they can mature and harm the range. Insect eaters, purple martins consume a lot of them every day. All kinds of flying insects, such as beetles, winged ants, flies, dragonflies, grasshoppers, crickets, moths, wasps, bees, cicadas, termites, and mayflies, are preferred food items.

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metagenomics helps researchers to better understand viral diversity. check all of the correct statements about this approach and what we have learned.

Answers

correct statements about metagenomics approach are:

a. In one liter of coastal water, there are 10 times more viruses than bacteria

b. Since only a small fraction of viruses cause disease in animals and plants, it is hard to isolate viruses.

The study of the structure and function of complete nucleotide sequences that have been isolated and analyzed from all of the organisms—typically microbes—in a bulk sample is known as metagenomics. For virus metagenomics, soil and water are good sources. As a non-targeted diagnostic and surveillance tool, clinical samples can also be used with metagenomics. Metagenomics provides invaluable insights into the virus-host interactions, epidemiology, ecology, and evolution of viruses across all ecosystems by enabling the study of these uncultivated viruses.

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A variety of factors influence enzyme activity. Substances that bind to the enzyme and interfere with substrate binding or catalysis are inhibitors. Identify the type of inhibition associated with each of the following descriptions and examples by sorting each item into the appropriate bin. Irreversible inhibition Competitive inhibition Noncompetitive inhibition Note: If you answer this question incorrectly, a single red X will appear indicating that one or more of the phrases are sorted incorrectly binding by the inhibitor malonate, which resembles the A on binds to succinate, binds to the decreases V max acetylcholinesterase or to the succinate dehydrogenase acetylcholinesterase-substrate active site complex DIPF permanently modifies the inhibitor may permanently binding by the inhibitor ydroxyl group of a modify an enzyme does not affect Vima Ser residue at the active site

Answers

Malonate is a competitive inhibitor of succinate dehydrogenase, which binds reversibly to the active site of the enzyme. An active site Ser residue's hydroxyl group is irreversibly modified by the irreversible inhibitor DIPF. Al³⁺ binds non-competitively to the acetylcholinesterase active site and reduces Vmax.

The substances that bind to enzymes and reduce their activity are known as enzyme inhibitors and the process is known as enzyme inhibition.

Competitive inhibition is the mechanism by which an inhibitor binds to the enzyme's active site and blocks substrate binding. The maximal reaction velocity under competitive inhibition does not vary. Therefore, in competitive inhibitions, binding by the inhibitor has no effect on the Vmax. Malonate works as a competitive inhibitor of succinate by competing with it for binding to the active site on the enzyme succinate dehydrogenase.

An inhibitor's ability to attach to both the enzyme and the substrate equally is known as noncompetitive inhibition, which lowers the enzyme's activity. Therefore, binding by the inhibitor results in a decrease in Vmax in non-competitive inhibitions. Non-competitive inhibition of acetylcholinesterase occurs in Al³⁺. The Al³⁺ binds to the acetylcholinesterase active site and decreases the enzyme's activity.

When an inhibitor binds to an enzyme, no alternative enzyme-substrate complex can form, resulting in irreversible inhibition. Diisopropyl phosphorofluoridate is known as DIPF. This kind of inhibitor is irreversible. As a result, the hydroxyl group of the Ser residue in the active site can be irreversibly modified.

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