Patient was treated with autologous cd34+ hematopoietic stem and progenitor cells transduced ex Vivo with self inactivating lentiviral vector encoding human ada. I can't understand what it is saying at all.​

Answers

Answer 1

The technique makes reference to a vector-based gene therapy in which the expression for a gene associated with Adenosine Deaminase Deficiency (ADA) is restored.

What is gene therapy?

Gene therapy refers to the genetic engineering methodologies to correct the defective expression of certain genes.

Gene therapy is divided into methods that use viral vectors to incorporate the defective nucleic acid (in this case lentiviral vector) or non-based vectors (e.g. polysomes or polycations).

In conclusion, the technique is a vector-based gene therapy to restore Adenosine Deaminase Deficiency (ADA).

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Related Questions

Please answer!! i need help so bad. please!!!

Answers

The purple kernel is dominant over the yellow kernel and hence it has the genotype of homozygous dominant PP.

What is Genotype?

Genotype may be defined as the ultimate combination of alleles of genes that are selected for specific studies.

If it has some offspring with purple kernels and some with yellow, the genotypes of the two parents are heterozygous dominant for the purple kernel, i.e. Pp and Pp.

And when these two parents are crossed with each other, the genotypes are PP, Pp, Pp, and pp. While the genotypic ratio is 1:2:1 (PP: Pp: pp), but the phenotypic ratio is 3:1 (Purple: Yellow).

Therefore, it is well described above.

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If the father is allergenic and the mother
is not then the chances for a son is
15%
30%
60%
0.9%

Answers

Answer:

I think the correct qnswer for this question is 50% but it is not given in the option so the correct answer is 30 %

Thank you.........

What is an anticodon?
the three bases on a tRNA that match up with mRNA
the three mRNA bases that code for an amino acid
the portion of DNA that codes for a protein
the bond between amino acids while they are in the ribosome

Answers

An anticodon refers to the the three bases on a tRNA that match up with mRNA; option A.

What is an anticodon?

An anticodon is a complementary triplet of nucleotides which is found in tRNA molecules.

The anticodons are complementary to codons which are the triplets of nucleotides found in mRNA which code for a particular amino acid.

In conclusion, anticodons are complementary to codons.

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Which of the statements is most accurate about how individual atoms produce light?

Answers

The concept of the photon emerged from experimentation with thermal radiation, electromagnetic radiation emitted as the result of a source’s temperature, which produces a continuous spectrum of energies.The photoelectric effect provided indisputable evidence for the existence of the photon and thus the particle-like behavior of electromagnetic radiation. However, more direct evidence was needed to verify the quantized nature of energy in all matter. In this section, we describe how observation of the interaction of atoms with visible light provided this evidence

Which method of microbial control does not rely on d naturing proteins or disrupting the cell membrane

Answers

Lyophilization

What is Lyophilization?

Freeze drying, often referred to as lyophilization or cryodesiccation, is a method of low temperature dehydration that entails freezing the product, releasing pressure, and then sublimating the ice. In Lyophilization it contrasts with dehydration caused by the majority of traditional methods, which use heat to evaporate water.

Stages of Lyophilization:

Pretreatment includes any method of treating the product prior to freezing. This may include concentrating the product, formulation revision (i.e., addition of components to increase stability, preserve appearance, and/or improve processing), decreasing a high-vapor-pressure solvent, or increasing the surface area.Freezing and annealing during the freezing stage, the material is cooled below its triple point, the temperature at which the solid, liquid, and gas phases of the material can coexist. The product needs to be frozen gradually to form larger crystals, or it can undergo annealing, which involves cycling the temperature up and down.Primary Drying Lowering the pressure (to a few millibars or less) and providing adequate heat to the substance causes the ice to sublimate during the primary drying phase.The secondary drying phase aims to remove unfrozen water molecules, since the ice was removed in the primary drying phase. This part of the freeze-drying process is governed by the material's adsorption isotherms.

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Fat digestion relies on which accessory organs

Answers

Fat digestion relies on which accessory organ is the Liver.

What is the feature of the accent organs of digestion?

Accent organs of digestion are organs that secrete materials wanted for the chemical digestion of meals but through which food does now not truly pass as it is digested. besides the liver, the important accessory organs of digestion are the gallbladder and pancreas.

Accent digestive organs or systems aid digestion physically and convey secretions that break down foodstuff inside the Gastrointestinal tract.

The organs that help in digestion include the teeth, tongue, gallbladder, salivary glands, liver, and pancreas.

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__ is a renewable form of energy that comes from plants

Answers

Answer:

Biomass

Explanation:

In most cases, it is organic waste. anything, including pig intestines, maize husks, and wood chips. The procedure can vary depending on what is burned specifically, but in a typical power plant arrangement, it is burned similarly to coal. Pollution (even if it is carbon neutral) and the plant's potential for intermittent feedstock supply, which reduces efficiency, are downsides. either carbon neutral or renewable In my opinion, it is renewable by definition. Although it is not carbon neutral, very little else is either. Solar and wind energy still have a carbon impact. Those still have a net gain even though they offset more carbon than their footprint (per current manufacturing). Although burning biomass has a positive carbon footprint, is it more carbon-neutral than burning coal and natural gas? Maybe. Burning biomass releases carbon dioxide into the atmosphere that has previously been stored. Through feedback processes, this sudden rise in carbon will lead to an increase in other GHGs. Cutting down young trees for this reason also eliminates a carbon sink, which doesn't replenish until 60+ years (or 100+ in certain cases). Other biomass sources have a quicker recovery time. It is possible for biomass to be net negative when combined with carbon capture. Its efficiency might be increased by using it directly for heating purposes. There are several factors to take into account while deciding whether to utilize it, such as which other sources it would actually counteract. Overall, it should be used sparingly and with continual consideration of the particulars.

where can Electrostatic Precipitators be used

Answers

The Electrostatic Precipitators are used in air pollution control and power-generating stations.

What is the Electrostatic Precipitator?

An electrostatic precipitator consists of a negative electrical charge (-) generator. The device emits the charge in polluting particles and these become negatively charged. The walls of the precipitator are positively charged and attract the particles, which are retained. This encounter is due to the attraction between opposite charges.

In this case, we can found Electrostatic Precipitators used in the removal and treatment of the flux of pollutants  and power-generating stations.

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List at least 10 ways to maintain health care at home / community.​

Answers

10 strategies for sustaining home or community-based healthcare are: consuming proper foods, maintaining a balanced diet, avoiding smoking and consuming alcohol, exercising on regular basis, taking necessary calories, Checking the blood pressure and other blood components on a routine basis, and using a mask or protection to prevent disease spread, and wash hands properly, maintain cleanliness in and outside the apartment, drink plenty of safe water.

Discussion about the strategies:

Consume a variety of foods, such as fruits, vegetables, legumes, nuts, and whole grains for healthcare.Limit your daily salt consumption to 5g, or roughly 1 teaspoon. It is simpler to do this by choosing low-sodium foods and by reducing the amount of salt, soy sauce, fish sauce, and other high-sodium condiments you use while cooking meals, removing salt from your meal table, avoiding salty snacks, and removing salt, spices, and condiments from your meal table.Less than 30% of our entire calorie consumption should come from fats. Necessary calories should be taken.There is no recommended safe amount of alcohol consumption. So, stay away from alcohol.The term "physical activity" refers to any skeletal muscle-driven movement that involves the use of energy. So, get moving.One term for high blood pressure is "silent killer". This is due to the fact that many people with hypertension could not be conscious of the issue as it might not show any symptoms. So be sure to check your blood pressure often.When you start to cough or sneeze, make sure your mouth is covered with a face shield or a tissue, and then dispose of it safely.Use bug repellent and dress in light-colored, long-sleeved shirts and slacks as a healthcare strategy. Use bed nets, door and window screens, and weekly cleanings to eliminate mosquito breeding grounds in your house.Take in a lot of clean water. Water-borne illnesses including typhoid, dysentery, hepatitis A, fever, and polio can spread through the use of contaminated water.The transmission of contagious diseases can be stopped by using clean hands. When the hands are obviously dirty, you should wash them by hand with soap and water or use an alcohol-based hand scrub.

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Where is ozone beneficial?
A. troposphere
B. stratosphere
C. mesosphere
D. thermosphere

Answers

I believe it should be the stratosphere :B:

A 10% glucose solution is placed in the thistle tube. The thistle tube is placed in a beaker that contains a 5% glucose solution. There is a differentially permeable membrane across the broad end of the tube, which is permeable to water but not to the sugar glucose. As diffusion occurs,

Answers

The 10% glucose solution will become less concentrated whereas the 5% solution will become more concentrated.

How, explain your answer briefly?

There are two glucose solutions having different amount of glucose in it which is separated from each other by a differentially permeable membrane. Through this membrane, glucose can not pass through it but water can diffuse through it due to its smaller size. Therefore, the water will diffuse from the 5% glucose solution toward the 10% glucose solution.

So less water is present at 5% solution after diffusion which make it more concentrated while on the other hand, 10% solution will become less concentrated as water will enter into it so we can conclude that 10% glucose solution will become less concentrated whereas the 5% solution will become more concentrated.

Thus, this could be the answer.

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Pls help it urgent. I’m clueless

Answers

Answer:

rg

Explanation:

rg

mr svedbergs jewelry store is transformed into a what before nick and caitlin are able to speak to him again

Answers

The thing which Svedberg's jewelry store is transformed into is rubble as it can be barely recognized.

What happened in Tesla's Attic?

Caitlin and Nick went to Svedberg's jewelry store to make an appraisal of a piece of jewelry that belonged to Caitlin's mother.

We can see from the complete text that the jewelry dealer, Svedberg recognizes the insignia on the jewelry and becomes instantly interested but the jewelry is a dangerous one, belonging to the Accelerati who are not to be trifled with.

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How is EPD (expected progeny difference) used in livestock selection and breeding practices?

Answers

EPDs are computed using production data that registered seedstock members have provided to the breed organizations. Based on ancestral data, individual performance data, and progeny data as they become available, this information is entered into statistical matrices to generate the estimated Page 2 breeding values of animals.

Question 4 of 10
Which phrase best describes the main goal of a human community?
A. To preserve culture and language
B. To meet needs through collective effort
C. To analyze group behavior through observation
D. To make and follow rules through political process
SUBMIT

Answers

Answer:

I guess the correct answer is option B

What is the typical sign that appears in the early ambulatory stage of Duchenne Muscular Dystrophy

Answers

The typical sign that appears in the early ambulatory stage of Duchenne Muscular Dystrophy are:

Constant muscle weakness that begins from the proximal muscles and pelvis and then affects voluntary muscles,The child loss interest in running, falling, toe walking, etc.Growing impairment with ADLs and mobility start around age 5 and unable to ambulate follows.

what is the early ambulatory DMD?

The early ambulatory DMD is the first thing that happens or that shows when a patient have symptoms of the above.

It is known to be the waddling gait, Gowers' sign, and it is one where the person might toe walking, and constant struggle when climbing the stairs.

How we save water during washing dishes??

Answers

use warm water, keep the dishes close, and skip the pre-rinse are some ways to save water.

How and why do scientists try to remove bias from their experimentation?

Answers

Answer:

The blind design should suffice.

Please help!! Will mark brainiest

In a balanced community, a population of prey can benefit from predators.

Which statement BEST describes how the population of mice can benefit from the snakes in this garden?

1. The snakes also consume moles, which allow the population of mice to increase

2. The snakes will consume only the mice best adapted to their environment.

3. The snakes provide an energy source for the mice.

4. The snakes keep the mice from overpopulating, which could deplete their resources

Answers

Answer:

4

Explanation:

Snakes make sure that mice population is controlled, so there is more food for other mice.

look at the picture

Answers

Answer:

D.

Explanation:

This is related to the moons pull on the ocean more though,

Answer:

I am not 100% sure, but I'm guessing it is the last option

Explanation:

This is because, in the experiment the air is interacting with the water and the only option which shows air (atmosphere) interacting with water (hydrosphere) is the last option.

Hope it helps!

What is importance of heat energy to humans

Answers

Answer:

Explanation:

there are many enzymes in human body that require heat energy to perform their actions

Using the following diagram, which image shows the absorption of the highest energy photon?

Answers

Answer:

Diagram D

Explanation:

When electrons absorb energy, they move to higher orbital levels. The highest energy levels are the furthest from the nucleus. More energy is needed to occupy higher energy levels. Therefore, the electron which must have absorbed the most energy is in Diagram D. In this diagram, the electron absorbs enough energy to move it from n = 1 to n = 4.

When electrons absorb energy, they move to higher energy levels. In the given question, option D shows maximum energy absorption as electrons move from n = 1 to n = 4. Thus, the correct option is D.

What is electron transition?

Electron transition is the transition of an electron from one energy level to another within an atom or artificial atom. In this, the electron "jumps" from one energy level to another, typically in a few nanoseconds or less. This transition is favored by the difference in energy in different energy levels.

When an electron absorbs energy, they move to higher energy orbital levels. The highest energy levels are the ones farthest from the nucleus and the lowest energy levels are the ones that are nearest to the nucleus. As more energy is required to stay at higher energy levels. Therefore, the electron must absorb the most energy.

In this diagram, option D denotes the highest energy photon as the electron absorbs enough energy to move from n = 1 to n = 4.

Therefore, the correct option is D.

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One reason that multiple approaches are often taken to answer a testable question is that scientists
have different educational backgrounds and experiences.
want to determine the single best way to find an answer.
often look for the quickest way to answer the question.
get tired of using the same approach every single time.

Answers

A testable question uses multiple approaches as the scientists have different educational backgrounds and experiences. Thus, option A is correct.

What is a testable question?

A testable question is a problem that can be answered and solved with the help of experimental design and through research studies. It uses the test and variables to compare the result of the experiment with the control group.

It uses multiple approaches to conclude the testable question as the scientists involved may be from various educational backgrounds and differs in experience over the subject work.

Therefore, multiple approaches are used to solve the testable question.

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Aristo was riding in a car and noticed a pond that was covered in algal blooms due to excess phosphorus in the water. which of these other features in the landscape could be the reason for the high levels of phosphorus?many carscow pasturesolar panelsforest

Answers

Cow pasture is the reason  for the high levels of phosphorus in the water resulting in algal blooms.

Algae blooms, also known as overgrowths of algae, occur quickly when phosphate and nitrogen levels are too high. Algal overgrowth burns oxygen while obstructing sunlight from reaching submerged plants.Although cow pasture (manure from cow dung) is frequently kept in enormous storage "lagoons," some of it unavoidably leaks into the groundwater and neighboring rivers, causing blue-green algae, or cyanobacteria, blooms.Commonly, runoff or soil erosion from fertilizer and manure introduces these nutrients. Toxic algal blooms may occur when these extra nutrients combine with hot sunny days. The blooms are harmful to people, animals, and fish.

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1. Nitrogen is essential nutrition in plant growth. But farmers who cultivate
leguminous plants like pea plants and grams do not apply nitrogen fertilizers
during cultivation. Why? How does this practice help the farmers?

Answers

Answer:

Explanation:

the leguminous plants fix nitrogen in their roots hence do not require nitrogenous fertilizer

This organism is a single cell that was isolated from the human body, has no nucleus, and was causing the patient to be ill.

Answers

This organism is a single cell that was isolated from the human body, has no nucleus, and was causing the patient to be ill, in this case is a bacteria.

What is the concept of bacteria?

Bacteria are single-celled prokaryotic organisms that are included in the Archaea and Bacteria Domain. Bacteria are fairly simple organisms and belong, according to Whitta's classification of five kingdoms, to the Monera Kingdom.

In this case, Bacteria are prokaryotic and unicellular organisms, that is, formed by a single cell, without a nucleus and with membrane-bound organelles.

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When this cell divides to form two cells, which diagram shows the most likely
result?

Answers

I am 90% sure it is a

WILL GIVE THANKS AND BRAINLIEST :)

6. Two different populations of similar organisms are considered separate species when they are _____ isolated.

Answers

When two populations of similar organisms are reproductively isolated, then we consider them as separate species.

Species are formed when there is reproductive isolation between the different populations of similar organisms. Reproductive isolation can happen due to several factors such as environmental problems and natural calamities. Sometimes, a barrier arises between the two populations due to which populations of similar organisms get separated and the individuals of each population reproduce within their population. With time, their genetic makeup changes and they become separate species. The two species can have many similar characteristics. But, they will have genetic variations. For example- Solanum tuberosum and Solanum melongena are two different species but they have some common characteristics.

Thus, when no reproduction occurs between the two populations from similar organisms, then they become different species.

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Harmful algal blooms are characterized by a rapid increase in the population of a type of algae that produces toxins. Toxins are chemicals that are poisonous to living things. The rapid reproduction of this type of algae is caused by the presence of sunlight, warm water, and an increase in the level of nutrients in the water. The nutrients come from farms that use chemicals to make their plants healthy. They are carried to lakes and rivers by runoff.

Suppose this scenario was modeled in the lab. How would the populations of the biotic factors be affected?

Answers

There will be a decrease in the population of the biotic factors as a result of the presence of the harmful algal blooms.

What are Biotic factors?

These are referred to the living components which are present in the ecosystem and examples include fish etc.

Presence of harmful algal blooms means there will be poisoning of the living organisms which will result in their death and reduction. This is therefore the ways in which the populations of the biotic factors will be affected.

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What are meristematic tissues? Mention its different types, its location in plant body

Answers

Answer:

tissue in body

Explanation:

they are tissues in the body

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