One example of an oncogene is ras. Ras is a G protein that is activated when growth factors bind to a G protein-coupled receptor. The mutated form of ras binds to GTP but does not allow the GTP to be broken down to GDP. Ras is involved in both the G 1 and G 2 checkpoints. What happens to cells that have this mutated form of ras

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Answer 1

Ras is involved in both the G1 and G2 checkpoints.Through the inhibition of cyclin-dependent kinase inhibitors (CKIs), such as p27 and p21, which would otherwise bind with and inhibit cyclin-dependent kinases, oncogenic RAS can enhance cell cycle advancement (CDKs). IgM).

Growth factors bind to cell surface receptors to promote cellular proliferation and/or differentiation.While some growth factors are unique to a particular cell type, others are highly adaptable and stimulate cellular division in a variety of oncogenic cell types. When growth factors attach to growth factor receptors, normal Ras is activated. Ras becomes GTP-bound when it is inhibitors, activating a signalling pathway that promotes cell division and proliferation.

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Related Questions

Zoom out as far as possible and locate the Ring of Fire on your map. Compare the location of the volcanoes in the Ring of Fire with the nearby plate boundaries. Using the plate boundaries legend, which type of boundary is most prevalent at the location of these volcanoes?

Answers

Note that the type of boundary most prevalent at these volcanoes is: "the Divergent/Transform Plate boundary. See the attached image showing the ring of fire.

What is the ring of fire?

The Ring of Fire is an area on the Pacific Ocean's rim where frequent volcanic eruptions and earthquakes occur. The Ring of Fire is a 40,000 km long and up to 500 km broad horseshoe-shaped ring.

The Ring of Fire, also known as the Circum-Pacific Belt, is a route that runs around the Pacific Ocean that is marked by active volcanoes and frequent earthquakes. The Ring of Fire is where the bulk of Earth's volcanoes and earthquakes occur.

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Which of these statements is true?
c. The best fossils are formed during a cataclysmic event.
a. Younger strata are usually nearer the surface.
d. Rock strata are formed by volcanic activity.
e. Water’s ability to erode rock helps to explain how fossils are formed.
b. More recent fossils are in the deepest

Answers

'Younger strata are usually nearer the surface' is the true statement.

What do you mean by Strata?

Strata is a term that refers to the various layers of a rock formation. The term is used in a variety of fields, including geology, archaeology, and petrology. It describes the various layers of sedimentary rock that have been formed over time, as well as the different types of sedimentary rock that can be found in a strata.

This statement is true because younger strata (layers of rock or sediment) are generally deposited more recently and are therefore closer to the surface than older strata. This is because over time, as the Earth's surface erodes and is reshaped by various natural forces, the most recently deposited layers tend to be more exposed.

Hence, Option B is correct.

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Correct form of question:

Which of these statements is true?

a. The best fossils are formed during a cataclysmic event.

b. Younger strata are usually nearer the surface.

c. Rock strata are formed by volcanic activity.

d. Water’s ability to erode rock helps to explain how fossils are formed.

e. More recent fossils are in the deepest.

Why do cells have different membrane carbonhydrates.

Answers

Answer: Carbohydrates on the cell membrane help cells function properly. Carbohydrates do this in two ways: helping cells recognize each other and providing protection for cells.

How the respiratory system and circulatory system work together to supply the body with oxygen and to remove waste from the body?

Answers

Together, the circulatory and respiratory systems assist eliminate waste carbon dioxide from the tissues and deliver oxygen to the tissue.

The respiratory system is the one that helps to inhale oxygen and exhale carbon dioxide. And the circulatory system is the system that helps to supply oxygen from the lungs to tissues and helps to remove carbon dioxide from the tissue via the lungs. Both these process helps to supply oxygen in this way and helps to remove carbon dioxide as a waste.

First, the oxygen inhaled will be transported to the lungs and this oxygen will be exchanged with the blood that brings the waste (CO₂) from the tissue via the heart. Then, the oxygen will be transported to the heart from where the oxygenated blood will be supplied to the tissues. And the waste from the tissue will be carried via deoxygenated blood.

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Compare and contrast the properties of oceanic crust and continental crust

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Oceanic crust is generally younger than continental crust, being less than 200 million years old. It is made of basaltic rock, which is denser and more mafic than the granitic rock found in continental crust. Oceanic crust is thinner and more dense than continental crust, with average thickness of about 6 kilometers compared to about 35 kilometers for continental crust. Oceanic crust is also less buoyant and more prone to subduction.

Continental crust is generally thicker and less dense than oceanic crust, and is composed mainly of granitic rock. It is much older than oceanic crust, having formed over billions of years, and is also more buoyant due to its lower density. Continental crust is less prone to subduction and therefore is more likely to form mountains and landforms. It is also much thicker, with an average thickness of about 35 kilometers.

The element phosphate can be found in which macromolecule(s):
O Protein
O Lipids
O Carbohydrates
O Nucleic Acids
O All of the above
O Proteins and Nucleic Acids only
O Carbohydrates and lipids only

Answers

MACROMOLECULE

The element phosphate can be found in nucleic acids.

Nucleic acids are macromolecules that are made up of nucleotides, which are the building blocks of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Each nucleotide consists of a sugar (either deoxyribose in DNA or ribose in RNA), a nitrogenous base (adenine, guanine, cytosine, or thymine in DNA; adenine, guanine, cytosine, or uracil in RNA), and a phosphate group. The phosphate group is an important component of the nucleotide and plays a key role in the structure and function of nucleic acids.

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It began much more simply, with the synchronization of bodies: running when others run, laughing when others laugh, crying when others cry, or yawning when others yawn.

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This section discusses a phenomenon called social synchronization, which is the propensity for people to mimic the actions and bodily reactions of those in their social group.

Running, laughing, sobbing, and yawning is only a few of the activities stated in the chapter that displays social synchrony.

According to research, social synchronization may take place in a wide range of contexts, such as sports teams, schools, and even online communities. It can also have a number of advantages, including enhancing group cohesion, lowering stress levels, and fostering happy feelings.

Social synchronization can be explained by the concept of social contagion, which is the spread of emotions and behaviors through a group, and the idea of mirror neurons, which are brain cells that respond to observed actions as if they were performed by the observer.

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Explain why fat-free potato chips fried in artificial fats contain fewer calories than those fried in natural fats.

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Fat-free potato chips fried in artificial fats contain fewer calories than those fried in natural fats because of the less fat content which are present in the product.

What is Artificial fat?

This is referred to as the type of fat which is created in an industrial process that adds hydrogen to liquid vegetable oils to make them more solid.

It also has less amount or percentage of fat which can be converted into calories by the body as fat on its own is also a major source if energy in the body but is usually metabolized slowly unlike carbohydrates which is metabolized faster.

This is therefore the major reason reason why fat-free potato chips fried in artificial fats contain fewer calories than those fried in natural fats thereby making it the correct choice.

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Compare the Giant's Causeway with Devils Tower. In what ways are these formations similar? In what ways are they different

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The Giant’s Causeway and Devils Tower are two naturally-formed rock formations that are both located in different parts of the world and are known for their respective geological and cultural significance. Despite their vastly different locations, these two formations have many similarities.

Both the Giant’s Causeway and Devils Tower were formed by volcanic activity. The Giant’s Causeway was formed approximately 60 million years ago when a volcanic eruption caused large basalt columns to form. Devils Tower was formed even earlier, around 50 million years ago, when a volcanic intrusion solidified and created the towering formation.

Both formations have also been carved by erosion over time. The Giant’s Causeway is made up of thousands of basalt columns, which have been carved by the sea into their current shape. Devils Tower is a single, towering column of igneous rock that is estimated to have been eroded by the Belle Fourche River over millions of years.

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What are the four features of bacteria?

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Bacteria are single-celled organisms having membrane-attached cell organelles instead of a true nucleus. The reason why bacteria may survive in harsh settings is because:

Energy generating enzymes

Endospores

Cell wall

Cyst

The primary property of the bacteria is their ability to develop a cyst, which protects them from harmful environmental elements. For instance, the prokaryotic organism can survive in both hypertonic and hypotonic conditions because to its cell wall. The bacteria also make endospores, which let them tolerate extremely high temperatures. The bacteria create cold shock proteins that help them withstand freezing temperatures. Bacteria are single-celled creatures that lack a genuine nucleus in favour of membrane-bound cell organelles. Because of the following factors, bacteria can withstand trying conditions:

enzymes that generate energy

Endospores are a kind of cell wall tumour.

The primary trait of bacteria is their ability to generate spores or cysts, which protects them from severe environmental conditions. The bacteria may also live in extremely hot or cold environments. The bacteria also need food, light, and water to live. Some bacteria have the ability to photosynthesize or feed on other living organisms.

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State a reason why the water lily lacks a waxy cuticle.

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WATER LILY

One reason why the water lily (Nymphaea spp.) lacks a waxy cuticle is because it is adapted to living in an aquatic environment. A waxy cuticle is a layer of cutin, a waterproof, protective coating found on the surface of plant leaves and stems. It helps to prevent water loss through evaporation and protect the plant from dehydration.

However, water lilies are adapted to living in an aquatic environment, where they are constantly surrounded by water. As a result, they do not need to worry about water loss through evaporation and do not have a waxy cuticle to prevent it. Instead, water lilies have evolved other mechanisms, such as thick, succulent leaves and stems, to help them absorb and store water.

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The water lily lacks a waxy cuticle because it is generally present in the water, so it does not have the adaptation to save water, so it does not have the waxy cuticle, while these are the adaptations of the desert plants.

What is the significance of the water lily?

The water lily is significant as it has an important role in aquatic ecosystems because it provides food for a wide variety of aquatic animals, such as insects and fish, while its roots can help stabilize shorelines, prevent erosion, and purify water by removing excess nutrients. Its seeds are of great interest to humans due to their high demands.

Hence, the water lily lacks a waxy cuticle because it is generally present in the water, so it does not have the adaptation to save water, so it does not have the waxy cuticle, while these are the adaptations of the desert plants.

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How fast do you administer IV epinephrine in NRP?

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It takes as fast as 45–60 seconds to provide the first dose of epinephrine with invasive neonatal resuscitation techniques like intubation or venous access. If the heart rate doesn't rise above 60 beats per minute after the initial dose, epinephrine can be given every 3 to 5 minutes.

Systematic evaluation of human infant and pertinent animal research comparing various epinephrine dosages, delivery methods, and delivery intervals in neonatal resuscitation to the (currently advised) intravenous (IV) administration of doses of 0.01 to 0.03 mg/kg given every 3 to 5 minutes. After being administered, epinephrine immediately starts to work. However, it can take 5–10 minutes for it to take full action. 

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Both ferns and cender trees rely on .............. To successfully fertilize themselves

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Answer:

Explanation:

Both ferns and cedar trees rely on wind-dispersed pollen to successfully fertilize themselves.

Ferns are a group of vascular plants that reproduce via spores. These spores are produced in clusters called sori, which are found on the underside of fern fronds. The spores are released from the sori, and are carried away by the wind to fertilize other ferns.

Cedar trees, which are coniferous trees, also rely on wind to disperse their pollen. The male and female cones of the tree are separate, with the male cones releasing pollen into the air which is carried by the wind to fertilize the female cones on the same or nearby trees.

Both ferns and cedar tree do not produce flowers or rely on animal vectors (like bees or butterflies) for pollen transport, they use the wind to move their reproductive cells and complete the fertilization process.

I need someone to explain this

Answers

Light energy is captured in the process of photosynthesis which stores the energy in organic molecules to be used in the process of respiration.

What is Photosynthesis?

This is referred to as the process in which green plants manufacture food in the presence of sunlight which is stored in the molecular bonds of organic molecules such as sugars.

It is used during the process of respiration by cells of the body and it involves the production of energy from the oxidation of complex organic substances as result of the body taking in oxygen and giving off carbon dioxide which is therefore the reason why they were chosen as the correct choices.

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How does natural selection lead to increases and decreases of specific traits?

Answers

More individuals with beneficial mutations will survive than those without it, and it will lead to an increase in the expression of those certain traits throughout the population through increases and decreases of specific traits.

Any modification to a species' structure or behavior that makes it more suited to surviving and procreating in its environment is referred to as an adaptation. Random mutations can cause the expression of particular features to become more prominent. Natural selection will result in an increase in the expression of specific features throughout the population since more people with advantageous mutations will survive than those without them.

Physical characteristics of an organism, such as the bill on a bird or the fur on a bear, are examples of structural adaptations. Behavioral adjustments make up the rest. Organisms use behavioral adaptations to help them survive. Bird migration and calls are two examples of behavioral adaptations.

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True or False. The bolded word in this sentence is used correctly.

I took at deep (BREATH) of fresh air.
O True
O False

GIVING BRAINLIEST!

Answers

Answer: True

Explanation:

It makes sense, I took a deep breath of fresh air. There's nothing.

By the way, you put at instead of "a". "I took at deep". It's supposed to be a instead of at

The _____ is located near the midline in the anterior portion of the thoracic cavity, posterior to the sternum and slightly superior to the heart.

Answers

Answer:

mediastinum is located near the midline

Megan and Juan drew the chart above to classify their organism. Review their picture and decide which organism they have. Justify your answer.

Answers

The organisms given here are paramecium, as per their structure.

What is a paramecium?

A genus of eukaryotic, unicellular ciliates known as Paramecium is frequently researched as a member of the ciliate group.

In stagnant basins and ponds, paramecia can be found widely in freshwater, brackish, and marine settings.

Typically, cells have an oval, elongate, foot, or cigar form. A rigid but elastic structure known as the pellicle surrounds the cell body.

This is made up of the inner membrane known as the epiplasm, a layer of flattened membrane-bound sacs known as alveoli, and the outside cell membrane (plasma membrane).

Thus, the organism is a paramecium.

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In a plant, having red flowers has the allele R, and having white flowers has the allele r. A plant with white flowers is crossed with another plant with an unknown genotype. One hundred percent of the offspring have the genotype Rr. What is the genotype of the unknown parent

Answers

Answer:

Explanation:

dominant - red - RR

recessive - white - rr

rr is crossed with an unknown genotype to form Rr,

hence, it can only be RR

rr    x    RR

r            R

     Rr

What religions allow premarital sex?

Answers

All major faiths condemn premarital sex, but Muslims appear to take Islam's prohibitions more seriously.

Adamczyk and Hayes wanted to know if individual choice or national culture was more to blame for the lower rate of premarital sex among Muslims. Premarital sex is a practise whereby two people engage in sexual activity before becoming married. Many cultures forbid it as a moral flaw, and many religions consider it to be sinful. In India, adult premarital activity is legal. Premarital sex between two individuals (above the age of 18) is not clearly prohibited in our charter.

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Summarize the function of water during chemiosmosis

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Chemiosmosis is the passage of ions down their electrochemical gradient over a structure bound to a semipermeable membrane.

Protons, also known as hydrogen ions, will diffuse from an area with a high proton concentration to a site with a low proton concentration. Using an electrochemical gradient of protons across a membrane, ATP can be produced.

The oxidation of water, which is "divided" into protons and oxygen by the oxygen-evolving complex, replaces the electrons lost from Photosystem II (OEC, also known as WOC, or the water-oxidizing complex). Ten photons must be absorbed by Photosystems I and II, four electrons must pass through the two photosystems, and two NADPH must be produced in order to create one molecule of diatomic oxygen (later used for carbon dioxide fixation in the Calvin Cycle).

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What effect would cyanide have on the electron transport chain ?

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This compound acts to inhibit cytochrome C oxidase, otherwise known as Complex IV of the electron transport chain. By inhibiting this complex, cyanide effectively halts the flow of electrons through the chain.

Cyanide poisons the mitochondrial electron transport chain within cells and renders the body unable to derive energy (adenosine triphosphate—ATP) from oxygen. Specifically, it binds to the a3 portion (complex IV) of cytochrome oxidase and prevents cells from using oxygen, causing rapid death.

Cyanide inhibits cytochrome c oxidase, the terminal oxidase of the mitochondrial respiratory pathway, therefore inhibiting the cell oxygen utilization and resulting in the condition of histotoxic anoxia.

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A glomerulus is Question 13 options: a) the expanded end of a nephron b) the source of erythropoietin c) attached to the collecting duct d) a knot of capillaries within the renal corpuscle e) the loop-shaped segment of the nephron

Answers

The correct option is D, A knot of capillaries within the renal corpuscle. Each nephron has a network of tiny blood vessels known as glomeruli that are encased in a sac known as Bowman's capsule.

The filtered waste product (urine) passes via microscopic tubes before being transported from the kidneys to the bladder by larger tubes known as ureters.

The glomerulus is the kidney's filtering unit, and it is made up of a network of capillaries and highly differentiated epithelial cells called podocytes, which govern the selective filtration of blood into an ultrafiltrate that will eventually become urine (Greka and Mundel, 2012).

Glomerulus is a tuft of blood capillaries nestled inside the glomerular capsule, which is situated at the end of each nephron. The glomerulus receives blood that is about to be filtered.

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What poisons cause muscle weakness?

Answers

Answer:

organophosphates and Quindine Poisoning

Explanation:

How often should IV IO epinephrine be administered during neonatal resuscitation if it is ineffective?

Answers

According to current NRP recommendations, a low-lying umbilical venous catheter (UVC) is the best way to administer epinephrine. This is followed by a 0.5–1 ml normal saline flush. During resuscitation, 1.0 mg (10 mL of a 1:10 000 solution) of epinephrine hydrochloride is advised to be administered intravenously (IV) every 3 to 5 minutes.

For the medication to reach the central compartment, each peripheral injection dose should be followed by a 20-mL flush of IV fluid. According to the most recent resuscitation recommendations, epinephrine should be administered if the newborn's heart rate is still below 60 beats per minute after 30 seconds of what appears to be effective ventilation with chest rise and 30 seconds of coordinated chest compressions and ventilations. 

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Why is permeable soil best for plants?

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Without sufficient Soil permeability, plants drown, suffocate, dehydrate, and starve. Healthy soil consists of sand, loam, and clay of varying sizes. The area between these bits are labeled macropores and micropores, depending on their size.

Soil permeability, the property of soil that allows water and air to pass through, is one of the most important properties to consider for fish farming. A pond built on impermeable soil loses little water to leach out. The more permeable the soil, the greater the penetration.

Soil permeability is important for proper plant growth and development and helps plants absorb minerals and sugars. Poor soil permeability also results in mud and stagnant water.

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What are 3 things that support the theory of evolution?

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Fossil evidence, biogeographical evidence, and anatomical evidence were some of the many types of evidence that Darwin utilised to support his theory of evolution by natural selection.

We'll examine a variety of sources of information to examine the evidence for evolution, including both anatomy and embryology. An evolutionary heritage can be determined by similar anatomical traits between organisms, including those that are only observable during embryonic development.

Molecule biology We can tell how closely related two creatures are by comparing and contrasting the "same" gene in those animals (i.e., a pair of homologous genes).

Biogeography - We can retrace the evolutionary history of species by looking at their geographic distribution.

Fossils - However, it confirms the existence of now-extinct species and occasionally captures potential "in-between" species. The fossil record is not a complete record of evolutionary history, forms on the path if present day species.

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which of the following is the most accurate comment on the earth's carrying capacity for people?
(a) K is smaller now than it was a thousand years ago.
(b)The human population is still a long way from K.
(c)Our technology has allowed us to keep increasing K.
(d)When it comes to humans, the concept of K is irrelevant.

Answers

We can keep raising K thanks to technology. The best assessment of how many people the earth can support is the following.

Whereabouts is the Earth?

Earth's location in the universe is determined by the Hercules Supercluster of galaxies. A supercluster is a group of galaxies bound together by gravity. Within this supercluster, a smaller group of galaxies called the Local Group includes us. Earth is situated in the Night Sky, the second-largest galactic in the Bike Club.

What does the actual name of Earth mean?

Contrary to common opinion, Earth lacks a globally recognized name. A common misinterpretation of the planet's scientifically known is "Terra." "Earth" is the planet's common surname as it is referred to in science.

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What is the importance of Mendel's conclusion?

Answers

Mendel concluded that traits can be divided into overt and latent traits. He named these dominant and recessive traits respectively. Dominant traits are traits that are inherited unchanged by hybridization.

Mendel developed his three principles of heredity to explain the transmission of hereditary traits before anyone knew that genes existed. Mendel's laws of inheritance​ greatly expanded our understanding of heredity and led to the development of new experimental methods.

Mendel's conclusion:

Genetic determinants are unique in nature. These determinants are called genes. Each parent has a pair of genes in each cell for each trait tested. F1 from a cross between two pure strains contains one allele with a dominant phenotype and one allele with a recessive phenotype.

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Drosophila (fruit flies) usually have long wings ( ) but mutations in two different genes can result in bent wings (bt) or vestigial wings (vg). 56) If flies that are heterozygous for both the bent wing gene and the vestigial wing gene are mated, what is the probability of offspring with bent wings only

Answers

The probability of offspring with bent wings only when flies that are heterozygous for both the bent wing gene and the vestigial wing gene are mated is 25%.

This is because in genetics, the probability of offspring having a certain genotype is determined by the Punnett square, which is used to calculate the genotypic ratios of possible offspring from a genetic cross. In this case, the Punnett square would reveal a 4x4 grid in which each parent has a 50% chance of contributing either the bent wing gene (bt) or the vestigial wing gene (vg) to the offspring.

The resulting combinations would be 25% BB (both parents contributing bt), 25% btVg (one parent contributing bt and the other contributing vg), 25% Vgbt (one parent contributing vg and the other contributing bt), and 25% VgVg (both parents contributing vg). Thus, the probability of offspring with bent wings only would be 25%.

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