How many different mutations in the CFTR gene that can cause cystic fibrosis have been identified?

Answers

Answer 1

The gene that encodes the CFTR protein is located on chromosome 7. Mutations in this gene lead to CF. Since the discovery of the CFTR gene in 1989, more than 2,500 mutations have been identified.

What is the function of CFTR gene?

The cystic fibrosis transmembrane conductance regulator (CFTR) protein helps to maintain the balance of salt and water on many surfaces in the body, such as the surface of the lung.

This mutation is caused by the deletion of three base pairs of the CFTR gene leading to the loss of an amino acid called phenylalanine, abbreviated F, in the CFTR protein.

In cystic fibrosis, a defect (mutation) in a gene — the cystic fibrosis transmembrane conductance regulator (CFTR) gene — changes a protein that regulates the movement of salt in and out of cells.

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Related Questions

example of a body part that is made up of scaffold is

Answers

Answer: Kidney

Explanation: scaffolds are structures that mimic real organs.

Answer:

One example of a body part that is made up of a scaffold is the skeleton.

Explanation:

The skeleton is a structural system in the body that provides support and protection for the body's organs and tissues. It is made up of bones, which are connected to one another by joints. The bones of the skeleton are arranged in a specific pattern and shape, forming a scaffold that supports the body and allows for movement.

Other examples of body parts that are made up of scaffolds include the respiratory system, the circulatory system, and the musculoskeletal system. These systems are made up of a network of tubes, vessels, and muscles that provide support and function to the body.

A student is comparing the cells of a prokaryote, an animal, and a plant. Identifying which two cell parts would show that the cell was a plant cell, and not a cell of a prokaryote or an animal?.

Answers

Answer:

A well-organized nucleus and chloroplasts can prove that it's a plant cell.

Explanation:

A prokaryotic cell will not have a well-organized nucleus as they just have strands of DNA. An animal cell will not have chloroplasts as they do not photosynthesize.

Two cell parts would show that the cell was a plant cell, and not a cell of a prokaryote or an animal are the Cell wall and chloroplast

In contrast to plant cells, animal cells lack centrioles, centrosomes (which are discussed under the cytoskeleton), numerous smaller vacuoles, and lysosomes. Unlike animal cells, plant cells have a large central vacuole and a cell wall made of cellulose, chloroplasts, plasmodesmata, and plastids used for storage. The nucleus of a prokaryote cell lacks a nuclear membrane, there are no organelles with a membrane around them (such as mitochondria or plastids), and the cell wall is usually present. It is made of peptidoglycan, and the nucleoid that contains the genetic material is there.

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What is the basic principle of gene regulation?

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Only a subset of a cell's genes are expressed or turned on. The phrase "expresses" or "turns on" indicates that that gene is creating protein. Gene regulation is the process of turning genes on and off.

A gene is a segment of DNA that encodes for a specific protein. DNA is the information database of the cell and is contained within the cell nucleus. It carries all of the crucial genetic instructions for generating the proteins that our cells require.

Each gene contains a unique collection of instructions, which are normally encoded and used for a certain function or protein.

Gene expression is the process by which the genetic blueprints of genes are employed to manage the protein synthesis required by our bodies to form cell structures. Structural genes are those that carry information essential for amino acid sequences. This procedure consists of two crucial steps:

Transcription- The messenger RNA is created in this phase with the help of RNA polymerase enzymes, culminating in the processing of mRNA molecules.

Translation- The primary purpose of mRNA is to direct protein synthesis, which results in post-translational modification of the protein molecules.

During gene expression, genetic codes from the DNA code are translated and transcriptionally transformed into proteins. The process of an organism's genetic makeup as physical features is depicted through genetic expression. The information travels from genes to proteins throughout this process.

Gene regulation differs depending on whether the organism is prokaryotic or eukaryotic. Eukaryotes include both multicellular and unicellular species such as mammals, fungi, plants, and protists that have cells with nuclei and other organelles. Prokaryotes are single-celled organisms that, like bacteria, lack a well-defined nucleus. Because eukaryotes have a well-defined nucleus and prokaryotes have not, the regulation of prokaryotic and eukaryotic transcription is fundamentally different.

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What is atherosclerosis related to?

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Atherosclerosis related to hardening of arteries.

Your arteries stiffen due to atherosclerosis, which is brought on by a slow accumulation of plaque. High cholesterol, high blood pressure, diabetes, smoking, obesity, inactivity, and a diet high in saturated fat are all risk factors. The signs of atherosclerosis may not manifest until you experience issues like a heart attack or stroke.

Plaque fragments have the potential to come loose, become lodged in your body, and cause harm. In a restricted artery, a blood clot might also develop. It might finally get loosened and pass through the artery.

The progression of atherosclerosis may start while you are a child.

Blood clots, carotid artery disease, Chronic kidney disease, coronary artery disease, heart attack, peripheral artery disease, stroke are the serious health problems and medical emergencies due to atherosclerosis.

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Eutherian mammals are uniquely defined by h
O aving fur.
O the young developing in a pouch.
O laying eggs.
O having a placenta.
O longer gestation periods because of more highly developed placentas. o

Answers

Laying eggs, Eutherian, placental, placental mammal, mammalian- any warm-blooded animal with skin that is somewhat or mostly covered in hair.

All mammals, with the exception of marsupials and the rare subclass of monotremes, give birth to live young that are fed milk. Any warm-blooded vertebrate with skin that is more or less covered with hair is referred to as eutherian, placental, placental mammal, or mammalian. All mammals, with the exception of the rare subclass of monotremes, give birth to live young that are fed milk. Except for monotremes and marsupials, all mammals fall under the category Eutheria.

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The genetic material of an organism has developed an error in replication, and this error is now part of the genotype in its
gamete cells. What could happen to the offspring of this organism?

A. Its offspring will revert to the genetic material of an evolutionary ancestor.

B. Its offspring will revert to the original genetic material from the previous generation.

C. Its offspring will inherit a completely different set of genetic material each generation.

D. Its offspring will inherit the error in replication if the error does not prevent reproduction.

Answers

Its offspring will inherit the error in the replication if the error does not prevent reproduction.

What are Gamete cells?

Gamete cells are reproductive cells that combine with another gamete cell during sexual reproduction. They contain half the genetic material of the organism, and when two gametes join together during fertilization, they form a zygote that contains the full genetic material of the organism. In humans, gamete cells are the sperm cells produced by males and the egg cells produced by females.

What is Reproduction?

Reproduction is the biological process by which the organisms create descendants. It is a fundamental feature of all known life; each individual organism exists as the result of reproduction. The known methods of reproduction are broadly grouped into two main types: sexual and asexual reproduction.

Hence, Option D is correct.

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how do the endocrine system and the nervous system complement each other in regulating the bodys functions

Answers

The Endocrine system sends hormones through the Circulatory system to control and coordinate body functions in much the same way as the nervous system uses tiny electrical signals. brain and complement each other, but they tend to work at different speeds

What is Stage 1 of photosynthesis called?

Answers

The light reactions are the first phase of photosynthesis.

Photosynthesis occurs in two phases. In phase I, water is used to transform solar energy into chemical energy, which is then stored in ATP and NADPH. As a waste product at this stage, oxygen is also released. In phase II, glucose is created by combining carbon dioxide with chemical energy from ATP and NADPH. In the cells of plants, organelles are called chloroplasts. In chloroplast contains grana are orderly stacks that are found in each chloroplast. Thylakoid membranes, which resemble sacs, make up the grana. Photosystems, which are collections of molecules that include the green pigment chlorophyll, are found in these membranes.

Hence, the light reaction in photosynthesis is used to create energy molecules.

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What is the relationship between chromosomes DNA genes and proteins?

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Chromosomes are made up of DNA, which contain the instructions for making proteins.

What do you mean by chromosomes?

Chromosomes are structures within the nucleus of cells that contain DNA. They are composed of protein and one molecule of DNA, and they contain the genetic information that determines an organism's inherited characteristics and traits.

Genes are made up of segments of DNA, and they provide the instructions for making proteins. Proteins are the molecules that do most of the work in the cells. They are made from the instructions found in DNA, which are stored in the chromosomes.

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The genetic material is duplicated during which stage of the cell cycle?a. the G phaseb. the S phasec. metaphase of mitosisd. cytokinesis

Answers

The cellular contents, excluding the chromosomes, and genetic material are duplicated during the G1 phase (Gap 1).

The process by which a cell prepares for cellular division is known as the cell cycle. The G1 phase, the S phase, the G2 phase, and the M phase are the four phases of the cell cycle.

The cell grows physically larger, copies organelles, and produces the molecular building blocks it will require in subsequent steps during the G1 phase, also known as the first gap phase. Cells accomplish the majority of their growth in G1; They produce proteins and organelles, which are necessary for normal DNA synthesis, as they grow in size. Proteins and RNAs are made here, and the centromere and other centrosome components are made here as well.

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Which of the following best describes an advantage of constructing habitat corridors?
A. Corridors connect habitats separated by fragmentation and connect wildlife populations.
B. Corridors prevent invasive species from traveling between protected habitats.
C. Corridors provide a safe passage for vehicles and allow humans to travel within wildlife preserves.
D. Corridors increase the amount of protected area that is not affected by humans.

Answers

The statement that best describes an advantage of constructing habitat corridors is that Corridors connect habitats separated by fragmentation and connect wildlife populations. That is option A.

What are habitat corridors?

Habitat corridors is defined as those wildlIfe corridors that allows for a connection between populations or habitats that are isolated with the aim of promotion of genetic diversity.

The importance of habitat corridors include the following:

increase food sources, provide valuable cover, decrease the chance of predation, and by reconnection of fragmented and isolated populations.

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How do I know if I have a recessive blue eye gene?

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The colour blue will always be recessive. If both parents have the blue allele, the child is likely to have blue eyes. If one parent has green eyes and the other has blue eyes, your child will almost certainly have green eyes because green is dominant over blue.

Which parent influences eye color?

Each parent will give their child one copy of their eye color gene. In this case, mother will pass  B and father will always pass b. This means that all of their children will be Bb with brown eyes. Each child will exhibit the dominant trait of their mother.

What is the most recessive eye color?

The dominant allele for brown eyes is always dominant over the other two alleles, and the dominant allele for green eyes is always dominant over the recessive allele for blue eyes.

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if you are a marine biologist who wants to study organisms that are capable of chemosynthesis, where would you collect organisms for your research?

Answers

If I were a marine biologist who wanted to study organisms that are capable of chemosynthesis, I would collect organisms for my research from a variety of deep ocean environments. These environments include hydrothermal vents, methane seeps, cold seeps, and whale falls.

Hydrothermal vents are located near tectonic boundaries in the deep ocean, and are characterized by high concentrations of hydrogen sulfide, a compound that serves as a source of energy for many organisms. These vents are home to a variety of chemosynthetic bacteria, including species of bacteria that can directly use hydrogen sulfide for chemosynthesis. I would collect organisms from hydrothermal vents by using submersible vehicles that can reach the depths at which these vents are found.

Methane seeps are another environment where chemosynthetic organisms are found. Methane is released from seeps, and this methane serves as a source of energy for chemosynthetic bacteria. I would collect organisms from methane seeps using submersible vehicles equipped with sampling devices, such as coring devices or sediment traps.

Cold seeps are another environment where chemosynthetic organisms are found. These seeps are characterized by the presence of methane, which is produced by bacteria. I would collect organisms from cold seeps using submersible vehicles equipped with sampling devices, such as coring devices or sediment traps.

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the uterus is a hollow, ________-shaped, muscular organ located in the anterior portion of the pelvic cavity, between the sacrum and the symphysis pubis, above the bladder and in front of the rectum.

Answers

Answer: Peared

Explanation:  The uterus, also known as the womb, is a hollow, muscular organ located in the pelvis between the bladder and rectum of individuals who are assigned female at birth. This pear-shaped organ plays a role in menstruation, pregnancy, and childbirth.

The lining of the uterus (endometrium) is the source of the blood and tissue shed each month during menstruation. After an egg released from an ovary has been fertilized, the resulting embryo implants in the uterus and fetal development begins.

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if a species contains 23% a in its dna, what is the percentage of guanine it would contain?

Answers

According to Chargaff's rule, if the percentage of A in the DNA of a species is 23%, the the amount of guanine will be 27%.

Chargaff's rule says that the in the DNA of any species the amount of guanine is equal to the amount of cytosine and the amount of adenine is equal to the amount of thymine. And also there exists a stoichiometric ratio in the purine and pyrimidine bases: A+G=T+C.

DNA stand for Deoxyribonucleic Acid. It is the genetic material found in majority of the organisms. There are various forms of DNA like A-type, B-type and Z-type. B-type DNA is the most common form which is a double-stranded helical molecule.

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I notice that my students do better on tests when I give them cookies beforehand. Write a hypothesis for an
experiment that could investigate this observation. whats the independent and dependent variable and constants and control groups and experimental group

Answers

Cookies from the constants brand kids will do better if they are given cookies before to the test.

What are the constants?

The kids will do better if they are given cookies before to the test. Cookies from the constants brand, DV kids with cookies, and IV cookies control.

Hypothesis for an experiment students do better on tests with independent and dependent variables and constants in groups.

Therefore, Group: Children not given cookies kids in an experimental group eating cookies.

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All somatic motor neurons produce __________.

Answers

Only acetylcholine. In addition to acting as a transmitter for the parasympathetic and somatic motor systems, acetylcholine (Ach) also has significant central nervous system effects.

At their connections with skeletal muscle fibers, all somatic motor neurons produce acetylcholine (ACh). The result is always excitatory, and the muscle fibers contract if the stimulation hits the threshold. At neuromuscular junctions, somatic motor neurons use the neurotransmitter acetylcholine to activate skeletal muscle fibers. In addition to controlling the body's voluntary motions, the somatic nervous system is also responsible charge of reflexes, a particular class of involuntary muscle reactions that are regulated by a cerebral pathway known as the reflex arc.

The complete question is:

All somatic motor neurons produce __________.

both epinephrine and norepinephrine

only norepinephrine

only acetylcholine

both acetylcholine and norepinephrine

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What happened when Mendel cross pollinated purple and white flowers?

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Mendel then combined these plant lines for purebreeding and noted the characteristics of the hybrid offspring. He discovered that every F1 hybrid of the first generation resembled one of the mother plants.

What will occur if a purple floral and a white flower are crossed?

Mendel observed that the F1 generation produced by hybridizing true-breeding  progeny plants only exhibited one feature of a characteristic. A true-breeding purple-flowering plant, for instance, might have been crossed with a truthful white-flowering plant.

What happened as a result of Mendel's cross-pollination?

However, Mendel found that crossing two distinct purebred plant varieties resulted in offspring that resembled either of the parents, not a combination of the two.

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In a biology lab, a student has been asked to identify smooth muscle by looking at samples on the table. The student correctly identifies the smooth muscle because it is the muscle in the shape of.

Answers

Answer: Bundles

Explanation:

The smooth muscle cells are small. These cells are spindle in shape and they do not exhibit striations. They appear in the form of bundles of thin and thick filaments.

The smooth muscles are involuntary muscles. The cells of these muscles have nucleus that is located in the center. These muscles contract automatically and slowly.

On the basis of the above description, the description of the smooth muscles can be related to the bundles.

Happy Holidays!!

Answer: d

Explanation: so u dont gotta read everything else the other person put

The hypothalamic-pituitary-gonadal axis ________.

Answers

The hypothalamic-pituitary-gonadal axis involves FSH and LH release.

The hypothalamic-pituitary-gonadal (HPG) axis (also known as the hypothalamic-pituitary-ovarian/testicular axis) refers to a hypothalamus, pituitary gland, as well as gonadal glands as a single entity. Because these glands frequently work together, physiologists and endocrinologists prefer to refer to them as a single system.

The HPG axis is important in the development as well as regulation of many body systems, including the immune and reproductive systems. Changes in this axis result in changes inside the hormones produced from each gland, which have a variety of local and systemic impacts on the body. In animals, the axis regulates development, reproduction, and ageing. GnRH-expressing neurons secrete gonadotropin-releasing hormone (GnRH) from the hypothalamus.

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The principal difference between tropical and temperate rainforests is the amount of precipitation they receive.
true
false

Answers

The principal difference between tropical and temperate rainforests is the amount of precipitation they receive. The statement is false.

Rainforests are classified into two types: tropical and temperate. Tropical rainforests are situated closer to the equator, when temperatures are higher. Temperate rainforests can be found near colder coastal locations north or south of the equator.

The tropical rainforest is a hot, damp ecosystem with year-round rain. It is famous for its lush plant canopies that form three distinct levels. The highest layer, or canopy, comprises gigantic trees that may reach heights of 75 meters (approximately 250 feet).

A vast variety of plants from this level are commonly used as houseplants. These plants adapt quickly to residential surroundings due to the limited quantity of sunshine and rainfall they receive. Wet leaves and leaf litter cover the rainforest's lowest layer or floor.

Due to a lack of sunshine, there are few vegetation on the forest floor. However, the hot, wet environment and all of the dead plant debris offer ideal circumstances for bacteria and other microbes to thrive.

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Where do germline mutations occur?

Answers

Answer:

Germline mutations occur in gamets.

FILL IN THE BLANK. typically, methylation of nucleosome n-terminal tails leads to ________.

Answers

Methylation of nucleosome n-terminal tails typically leads to transcriptional repression.

What is methylation?

Methylation is a chemical modification that involves the addition of a methyl group (-CH3) to a molecule. In the case of nucleosomes, the n-terminal tails are proteins that extend from the nucleosome and are involved in regulating gene expression.

Methylation of these tails can prevent transcription factors from binding to DNA and activating transcription, resulting in transcriptional repression. This process is important for controlling gene expression and maintaining genomic stability.

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how does the sodium-potassium pump help maintain the resting membrane potential? choose the correct option. group of answer choices moves potassium against its concentration gradient. moves sodium against its concentration gradient. moves potassium ions in and sodium ions out. moves sodium ions in and potassium ions out.

Answers

The sodium-potassium pump maintains the resting membrane potential by moving sodium ions out and potassium ions into the cell membrane.

By exchanging three intracellular potassium ions for two extracellular sodium ions, the sodium-potassium pump contributes to the maintenance of the resting membrane potential.

The sodium-potassium pump constantly progresses three sodium ions are transported out of the cell for every two potassium ions it shifts in. As a result, it retains the huge potassium ion gradient across the membrane, which serves as the foundation for resting membrane potential.

Sodium and potassium ions are moved by the sodium-potassium pump system against huge concentration gradients. It flushes three sodium ions are transported and into the extracellular fluid while moving two potassium ions into the cell where potassium levels are elevated.

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How do clams move without a brain?

Answers

Clams do not have a centralized brain but they do possess a nervous system with a few nerve cells that regulate their movement and other body functions as well.

Clams are the animals that belong to the phylum Mollusca. They possess two valves and hence are also called bivalves. Some species of clams are edible as well. The clams are found inside the oceans on the sandy floor of the water.

Brain is the centralized organ of the nervous system found in various organisms like vertebrates. It is responsible for the regulation of the functions and activities of the organism's body.

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Trace the auditory projection pathway from start to finish by placing these structures in order, starting with the nerve leaving the inner ear.

1. Cochlear nerve
2. Cochlear nuclei of medulla
3. Inferior colliculi
4. Thalamus
5. Primary auditory cortex

Answers

The auditory projection pathway from start to finish by placing these structures in order, starting with the nerve leaving the inner ear the correct option is 5. Primary auditory cortex.

The vestibulocochlear nerve carries information from the receptors in the inner ear's organ of Corte (cochlear hair cells) to the brain. For conscious perception, this route ultimately connects to the primary auditory cortex. Additionally, there is concurrent unconscious processing of auditory information.

The first order neurons' cell bodies are housed in the spiral ganglion. These neurons go through the osseous spiral lamina and get input from hair cells in the Organ of Corte .The cochlear nerve is primarily made up of their core axons.

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.

Classification of mammals

Answers

Mammalia are animals that belong to the class Mammalia. Mammals are one of the most evolved vertebrate species in the animal kingdom.

They are found all over the world and have adapted well to their surroundings, which include oceans, deserts, and polar regions, as well as rainforests and rivers. Let us take a closer look at the characteristics and classifications of the Mammalia class of animals.

Classification of mammals

1. Mammals are warm-blooded creatures that give birth to their young.

2. They are the most common type of animal found in almost all habitats.

3. They have mammary glands, which aid in the production of milk to feed their young.

4. The presence of a brain region known as the Neocortex

5. Their skin contains oil glands (sebaceous glands) as well as sweat       glands sudoriferous glands).

6. The fur of hair that covers the body and aids animals in adapting to their surroundings.

7. They are heterodont, which means they have different types of teeth.

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Why i it important for the oxygen that enter your bloodtream to reach your cell?

Answers

It is important for the oxygen that enters your bloodstream to reach your cell in order to reach every part of the body to fulfill the oxygen demand.

All red blood cells contain a red pigment known as hemoglobin. Hemoglobin is where oxygen binds and is transported throughout the body. The oxygen that is inhaled (breathed in) is carried through the bloodstream by red blood cells in tiny blood vessels in the lung to all parts of the body.

For metabolism, which produces carbon dioxide as a waste product, the cells require oxygen. The blood plasma transports the carbon dioxide back to the lungs via the bloodstream after it is absorbed from the cells and some of it binds to hemoglobin. When we exhale, it leaves the body there.

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(complete question)

Why it is important for the oxygen that enters your bloodstream to reach your cell?

Which of the following outcomes will most likely result from the irreversible binding of gdp to the g protein? responses

Answers

Increased intracellular glycogen concentration is the most likely outcome of GDP's irreversible binding to the G protein.

G proteins, sometimes referred to as guanine nucleotide-binding proteins, are a family of proteins that function as molecular switches within cells, relaying signals from a range of stimuli outside a cell to its interior. The G protein is made inactive when GDP binds to it in an irreversible manner. GTP initiates the protein by switching the GDP, and the G protein subsequently releases its signal. The non-response to norepinephrine binding and to the beta-adrenergic receptor, which prevents the G protein alpha subunit from being separated, causes a rise in the intracellular concentration of glycogen.

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What is an allergic reaction ?

Answers

Answer:

Allergies are your body’s reaction to a substance it views as a harmful

Explanation:

“invader.” For example, coming into contact with what is normally a harmless substance, such as pollen, might cause your immune system (your body’s defense system) to react. Substances that cause these reactions are called allergens.

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