Give reason why the permeability of both the membrane is same for fatty acid? ​

Answers

Answer 1

Answer:

Because of the amphipathicity and conical molecular shape of fatty acids.

Explanation

They can efficiently incorporate into lipid membranes and disturb membrane integrity, chain packing, and lateral pressure profile. These phenomena affect both model membranes as well as biological membranes. We investigated the feasibility of exploiting fatty acids as permeability enhancers in drug delivery systems for enhancing drug release from liposomal carriers and drug uptake by target cells. Saturated fatty acids, with acyl chain length from C8 to C20, were tested using model drug delivery liposomes of 1,2- dipalmitoyl-sn-glycerol-3-phosphocholine (DPPC) and the breast cancer MCF-7 cell line as a model cell. A calcein release assay demonstrated a reduction in the membrane permeability barrier of the DPPC, proportionally to the length of the fatty acid. Differential scanning calorimetry (DSC) and dynamic light scattering (DLS) experiments revealed that C12 to C20 fatty acids could stabilize DPPC liposomal bilayers and induce large structures, probably due to liposome aggregation and bilayer morphological changes. On the other hand, the short fatty acids C8 and C10 tend to destabilize the bilayers and only moderately cause the formation of large structures. The effect of fatty acids on DPPC liposomes was not completely transferrable to the MCF-7 cell line. Using cytotoxicity assays, the cells were relatively insensitive to the fatty acids at apoptotic sub-millimolar concentrations. Increasing the fatty acid concentration to few millimolar substantially reduced the viability of the cells, most likely via the induction of necrosis and cell lysis. A bioluminescence living-cell-based luciferase assay showed that saturated fatty acids in sub-cytotoxic concentrations could not reduce the permeability barrier of cell membranes. Our results confirm that the membrane perturbing effect of fatty acids on model membranes cannot simply be carried over to biological membranes of live cells.


Related Questions

How are organelles in a plant cell similar to organs in the human body? How are they different? Explain your answer.

Answers

Answer: The main difference between organ and organelle is that organ is a large part of an organism, composed of tissues which perform similar functions whereas organelle is a specialized structure found inside cells, which carries out a specific life process. Organelles form cells.

Why is flower is reproductive organ​

Answers

Answer:

The primary purpose of a flower is reproduction. Since the flowers are the reproductive organs of plant, they mediate the joining of the sperm, contained within pollen, to the ovules — contained in the ovary. Pollination is the movement of pollen from the anthers to the stigma.

What is the role of oxygen in cellular respiration?

It provides electrons for the electron transport chain.
It combines with carbon monoxide to form carbon dioxide.
It is needed for the production of light and heat.
It is the final electron acceptor for the electron transport chain.

Answers

Answer:

it combines with carbon monoxide to carbon dioxide

What determines the temperature of a layer of the atmosphere

Answers

Answer:

How far down the layer is

Explanation:

yeah

Why is there no such thing as being a “carrier” of an autosomal dominant disorder?

Answers

If it’s a dominant disorder it will always show up no matter what. So because of that you can’t be a “carrier” because to be a carrier it must be a recessive gene that doesn’t show up

8. Which of these is not a possible effect of the destruction of the
rain forest?
O A. drought
O B. crop failure
O c. more oxygen in the air
O D. increase in carbon dioxide in air

Answers

Answer:

drought

Explanation:

droughts are bad for the rain forests without water some plants can die

drought is not a possible effect of the destruction of the rain forest

Can someone help me with this question?

Answers

Answer:

the answer is A

Explanation:

hope it helps!!!

Period of a wave refers to...

Answers

Answer:

The period of a wave is the time for a particle on a medium to make one complete vibrational cycle. Period, being a time, is measured in units of time such as seconds, hours, days or years. The period of orbit for the Earth around the Sun is approximately 365 days; it takes 365 days for the Earth to complete a cycle. The period of a wave is the time for a particle on a medium to make one complete vibrational cycle. Period, being a time, is measured in units of time such as seconds, hours, days or years. The period of orbit for the Earth around the Sun is approximately 365 days; it takes 365 days for the Earth to complete a cycle.

Explanation:

it's C

Write 2 organisms that would have the most similar DNA.

Answers

Answer:

I think ... maybe ... dog and wolf?

Explanation:

because dog is just the domesticated version of wolf, then this may be possible - but this is just a very basic answer. other answers like chicken and dinosaur may be true as well depending on how specific your question is.

A photomicrograph of onion root tip cells during mitosis is shown below.
Staphoto.com/Alan John ander
Which phase of mitosis is occurring in the cell indicated by the arrow?
F Prophase
G Metaphase
H Anaphase
Talonha

Answers

Nut in you..........

How many food chains are in this food web?

Answers

Answer:

There are 8 food chains

Explanation:

in the experiment it is important to make measurements that are both precise and accurate
which of these measurements of time is the most precise
5.1 second s
5.14 second s
5 second s.​

Answers

Answer:

5 second s.

Explanation:

The base unit for time is the second (the other SI units are: metre for length, kilogram for mass, ampere for electric current, kelvin for temperature, candela for luminous intensity, and mole for the amount of substance). The second can be abbreviated as s or sec.

5.14 seconds

Explanation:

It gives a more specific time compared to 5.1 & 5

Question 3 of 20 -
0000 UNIT SCI07 408 SLPS2021
Question: 1-3
A biologist describes two modern-day species as "sharing a common ancestor." What does it mean when two species share a common ancestor?
Both species evolved from one species that lived in the past
One of the species evolved into the other species
The two species are actually the same species with genetic variation
The two species reproduced with one another and formed a common ancestor

Answers

Answer: C. is your answer

Explanation: It means the species shared a common ancestor in the recent past.

An organism's physical appearance is called?​

Answers

Answer: phenotype. An organism's physical appearance, or visible traits. genotype. An organism's genetic makeup, or allele combinations.

The physical appearance of an organism is called its phenotype.

What is the term used to describe an organism's physical appearance?

An organism's physical appearance also known as its phenotype refers to the observable characteristics that result from the interaction between its genetic makeup (genotype) and environmental influences. These traits can include features such as size, shape, color, and behavior.

The phenotype is the manifestation of an organism's genes and how they are expressed and it vary both within and between species. Studying phenotypes is important for understanding genetic inheritance, evolution and the overall diversity of life on Earth.

Read more about phenotype

brainly.com/question/902712

#SPJ6

Which organisms are producers?


Select all correct answers.

a. mushrooms
b. frog
c. grass
d. tree

Answers

Answer:

Grass and tree

A producer is a living thing that makes its own food. All food chains begin with producers.

( I am in LOVE with your pfp <3 )

Grass and tree. Mushrooms are composers and frogs do not prepare foods by themselves. (Btw love your nagito pfp) :)

I am a single-celled, prokaryotic organism that lives in the large intestines of mammals. I reproduce asexually by binary fission and can reproduce very quickly.

Answers

Answer: Kingdom:Eubacteria

organism name: kelp

Explanation: its kelp in the kingdom classification bacteria

Answer:

Escherichia coli.

Explanation:

Escherichia coli (E. coli) is a gram negative, rod shaped and facultative anaerobic bacterium that lives in large intestines of mammals. It is unicellular or single celled and prokaryotic organism. It reproduces asexually by binary fission.

It does not have nuclues or membrane bound organelbecause it is prokaryotic.

Therefore,

Escherichia coli lives inside large intestines of mammals.

Do the positive charges of calcium ions and sodium ions make these ions more likely to move into or out of the cell?

Answers

Answer:

Yes.

Explanation:

Yes, the positive charges on both calcium ions and sodium ions will responsible for the movement of these ions into or out of the cell because the membrane has negative charge which attract these positively charged calcium ions and potassium ions. These difference concentrations of sodium and potassium in the cell are due to the activity of cell membrane active transport system which moves sodium out of the cell and potassium into it.

Yes, the positive charges of calcium ions and sodium ions make these ions more likely to move into or out of the cell.

What do you mean by Diffusion?

Diffusion may be defined as a process resulting from the random motion of molecules by which there is a net flow of matter from a region of high concentration to a region of low concentration.

The membrane of a cell possesses a negative charge, so it attracts these positive charge ions and makes a concentration difference that leads to the process of active transport through which sodium moves out of the cell and potassium into it.

Therefore, Yes, the positive charges of calcium ions and sodium ions make these ions more likely to move into or out of the cell.

To learn more about Diffusion, refer to the link:

https://brainly.com/question/94094

Identify one environmental factor that could cause a base sequence in
DNA to be changed to a different base sequence.

Answers

Explanation:

Environmental exposure to certain chemicals, ultraviolet radiation, or other external factors.

Environmental exposure to certain chemicals, ultraviolet radiation, or other external factors can also cause DNA to change. These external agents of genetic change are called mutagens. Hope this helps! Mark brainly please!

If the pig is on its back, the one doing dissection would say the pig is on the
surface.
dosral
ventral
medial
lateral

Answers

Answer:

Ventral

Explanation:

This is because when you want to dissect a pig, it's back is place on a dissecting tray and it's belly side is up which is the ventral side. With the ventral side, dissection will be easy and the major organs and systems can be observed easily as they will be rightly viewed because they are obvious and rightly placed at belly side up.

Is it more likely that the T. Rex would have a 3-chambered heart or a 4-chambered heart and why?

Question 14 options:

A 3-chambered heart because the caiman also has a 3-chambered heart and the T. Rex is most closely related to the caiman.


A 3-chambered heart because the parrot has a 3-chambered heart and the parrot is most closely related to the T. Rex.


A 4-chambered heart because the caiman also has a 4-chambered heart and the T. Rex is most closely related to the caiman.


A 4-chambered heart because the parrot has a 4-chambered heart and the parrot is most closely related to the T. Rex.

Answers

B

boi what class are you in

Matching: Brain Functions

Answers

Answer:

Movement: Parietal

Conscious thought: Cerebral Cortex

Personality: Frontal

Speech/language: Cerebrum

Vision: Occipital

Memory: Temporal

Explanation:

The frontal lobe is important for cognitive functions and control of voluntary movement or activity. The parietal lobe processes information about temperature, taste, touch and movement, while the occipital lobe is primarily responsible for vision. The temporal lobe processes memories, integrating them with sensations of taste, sound, sight and touch.

Sorry I took so long, kept second-guessing myself, apologies if my response is faulty or incorrect. Have a good day/night! :}

what are the many little branches of the respiratory system?

Answers

bronchioles

air enters the respiratory system through the nose and mouth hope that helps :D

What are small organelles found in large numbers in the cytoplasm of a cell called?
A. Vacuole
B. Mitochondria
C. Ribosomes
D. Chloroplast

Answers

Answer: A. Vacuole

Explanation: :)

Answer: Mitochondria

Explanation:

What can you tell about the sex of this person where the chromosomes came from?

Answers

Answer:

Females have two X chromosomes in their cells, while males have both X and a Y chromosomes in their cells. Egg cells all contain an X chromosome, while sperm cells contain an X or Y chromosome. This arrangement means that it is the male that determines the sex of the offspring when fertilization occurs.

Explanation:

PLEASE HELPPP!!! I'll give brainliest!
Two atoms have the same number of protons but different numbers of neutrons. These atoms are:
A. electrons
B. isotopes
C. molecules
D. radiation

tysm!

Answers

Answer:

isotopes

Explanation:

If two atoms have different numbers of protons, they are different elements. However, if two atoms have the same number of protons, but different numbers of neutrons we refer to them as isotopes. Two terms we use to identify nuclides (isotopes) are atomic number and mass number.

PLZ, PLZ, PLZ HELP! NEED NOW!

Answers

Answer:

the answer is sugar buddy

Explanation:

Answer:

It's sugar. Glucose is the sugar in plants.

Meanwhile the ovary itself releases a hormone called estrogen which causes the uterine lining to increase in thickness.The uterine lining becomes thicker so that the fertilized egg can attach to it

Answers

Answer:

Meanwhile, the ovary itself releases a hormone called estrogen which causes the uterine lining to increase in thickness. The uterine lining becomes thicker so that the fertilized egg can attach to it. It is correct.

Explanation:

The hypothalamus, which is in the brain, releases a hormone called Gonadotrophin Release Hormone (GnRH). GnRH travels to the hypophysis, which is a gland located in the lower part of the skull. The GnRH makes the hypophysis release a hormone called Follicle Stimulant Hormone (FSH). This hormone travels to the ovaries, making it release estrogen. This hormone is in high concentrations during the 4th or 6th day of the cycle up to the 14th day, which is when ovulation happens. Estrogens make the endometrium, which is the outer layer of the uterus, grow making it thicker to prepare itself to attach the fertilized egg and provide to it the necessary nutrients to grow.

If the fertilization does not happen, the thickened endometrium will be expelled from the uterus some days later during menstruation.

In females, the uterine lining is at the site of fertilized egg attachment. The attachment of the fertilized egg makes the lining thicker.

What is the role of estrogen in uterine lining shedding?

The estrogen hormone is produced by the ovaries of females. The hormonal cycle with rising, estrogen, and progression causes the menstrual cycle.

The non-fertilized egg triggers the release of estrogen, and the uterine line sheds off.

However, the fertilization of the egg results in a decreased signal of estrogen in the female body, and the uterine lining becomes thick without shedding.

Thus, the statement about the thickening of the uterine lining with the fertilization of the egg is correct.

Learn more about the fertilization of eggs here.

https://brainly.com/question/11194250


Which model represents a possible chemical reaction

Answers

Answer: A I think

Explanation: I'am really sorry if i'am wrong

please help i’ll give brainliest

Answers

Answer:

its the second answer

Explanation:

Can anyone help me with these please

Answers

Answer:

6. Current = 8.33 Amps

7. Energy = 1200 Joules

Explanation:

Given the following data;

6. Power = 1000 Watts

Voltage = 120 Volts

To find the current flowing through;

Power = current * voltage

1000 = current * 120

Current = 1000/120

Current = 8.33 Amps

7. Power = 900 Watts

Time = 45 minutes to hours = 45/60 = 0.75 hours

To find the energy consumption;

Energy = power/time

Energy = 900/0.75

Energy = 1200 Joules

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