A child is born with hemophilia (inherited as an X-linked recessive) and Klinefelter's syndrome to parents who both have normal blood clotting. In which parent (mother or father) and during which round of meiosis (I or II) did the nondisjunction event occur

Answers

Answer 1

Answer:

mother  

Explanation:

Hemophilia is a sex-linked recessive disorder caused by a mutation in one of the genes responsible for encoding the clotting factor proteins (factor VIII or factor IX), which are located on the X chromosome. Moreover, the Klinefelter syndrome is caused by men having an additional X chromosome. In this case, the nondisjunction occurred from the mother because her gamete included an extra X, it is for that reason that all genes localized on the X chromosome, including the defective gene involved in hemophilia, can cause all of her sons to be affected by the disease in some generation. Thus, sister chromatids did not separate during meiosis (Anaphase II) and caused two copies of the defective allele for the hemophilia trait.


Related Questions

What result allowed Dintzis to conclude that proteins are synthesized from the N terminus to C terminus

Answers

Answer:

The more newly synthesized peptides had greater levels of radiolabeled H

Explanation:

Using immature red blood cells (reticulocytes), Dintzis showed that polypeptide chains of hemoglobin were created from N-terminal to the C terminus during translation. Dintzis labeled with radioactive amino acids that were being actively translated, subsequently digested the translated proteins with trypsin and finally determined the amount of tryptic protein fragments. From this experiment, Dintzis observed that the radioactive products were concentrated in the C-terminus (i.e., labeled amino acids appeared first in the C terminal tryptic peptides), thereby showing that the direction of protein synthesis is from the N terminus to the C terminus.

Define Vascular tissue?

Answers

Answer:

Vascular tissue is a complex conducting tissue found in vascular plants that is made up of several cell types. The xylem and phloem are the two main components of vascular tissue. Internally, these two tissues carry fluid and nutrients.

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How to get Live Imaging of the Cellular Genome via CRISPR System?

The spatiotemporal organization of chromatin structure plays a critical role in regulating lineage-specific gene expression during cellular differentiation and embryonic development, via contributing to the functional output of the genome, which can be dynamically amplified or suppressed. However, there is little known about how the genomes being modified and how their structural organization regulating function output.

Answers

Answer:

a catalytically inactive Cas9 enzyme (dCas9) is fused to fluorescent labels (e.g., GFP)

Explanation:

The CRISPR-Cas9 genome editing system consists of two parts: 1- a Caspase enzyme called 'Cas9' with catalytic activity that cuts DNA strands by hydrolyzing phosphodiester bonds, and 2-a single guide RNA (sgRNA) that directs Cas9 to target sites with complementarity to nucleotides of the sgRNA in order to edit these sequences. Using a catalytically dead Cas9 (dCas9) it is possible to repurpose the CRISPR-Cas9 system, for example, by fusing dCas9 to epigenetic enzymes for epigenome editing or by fusing dCas9 to the Green Fluorescent Protein (GFP) for imaging of the cellular genome. Thus, it is possible to use dCas9 to create a customizable DNA labeler that can be complemented with a fluorescence microscope and thus track multiple genomic loci in living cells.

What happens to animals because of plastic trash in the ocean ?

Answers

Answer:

They suffocate and choke because of the plastic waste, they also feel trapped in there and sometimes smaller animals get stuck in there

Answer:

Fish, seabirds, sea turtles, and marine mammals can become entangled in or ingest plastic debris, causing suffocation, starvation, and drowning. ... Plastic waste kills up to a million seabirds a year. As with sea turtles, when seabirds ingest plastic, it takes up room in their stomachs, sometimes causing starvation.

Explanation:

100 POINTS!! Please answer all questions, will report you if you don't give a serious answer

Answers

Answer:

1. b

2. l

3. i

4. c

5. k

6. y

Explanation:

___ A mismatched base pair during DNA replication B. Photoreactive repair ___ A thymine dimer in a bacterial cell A C. NHEJ repair ___ A mismatched base pair that occurred after DNA replication D. Base excision repair ___ A double strand break in G1 (cell does not care about precise repair) E. HR repair ___ A thymine dimer in a eukaryotic cell F. SDSA repair ___ A double strand break in G1 (cell does care about precise repair)

Answers

Answer:

Explanation:

●photoreactive repair - A thymine dimer in a bacterial

●SDSA -A mismatched base pair during DNA replication

●. Photoreactive repair - A thymine dimer in a eukaryotic cell

● NHEJ repair- double strand break in G1 (cell does care about precise repair)

In the picture below the purple circles represent salt molecules. Which way would
the water molecules move across the membrane

Right to left toward the higher concentration of salt

Left to right away from the higher concentration of Salt

Answers

Left to right away from the higher concentration of salt. Fluids try to be in balance, with equal distribution of what’s dissolved in them.

Help please! The question is in the image below

Answers

Answer: A. The cells produced sugar and oxygen during photosynthesis

Explanation: Plants today make use of this same trait, absorbing the sun's energy and air to create food (sugar) and oxygen (as a by-product)

What is the answer to number 1

Answers

Answer:

TTT GCC AGT

Explanation:

what kind of graph is this?​

Answers

Answer:

Explanation:

financial chart

Financial chart:):):):););););)

According to Darwin, ______ in species could result from many ______ over long periods of time.

A. population growth; births
B. big changes; small changes
C. mating; interactions
D. xtinction; deaths

Answers

According to Darwin, [tex]\sf\purple{big\:changes}[/tex] in species could result from many [tex]\sf\pink{small\:changes}[/tex] over long periods of time.

B. big changes; small changes

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Which micro-nutrient is NOT manufactured by living things?

A) Vitamins
B) Carbohydrates
C) Minerals
D) Fats ​

Answers

Answer:

Minerals is the micro-nutrient is not manufactured by living things

Most of the solar radiation absorbed by Earth's surface is later radiated back into space as to which type of electromagnetic radiation?"

Answers

Answer:

The sun's visible wavelengths of radiation pass easily through the atmosphere and reach Earth. Approximately 51% of this sunlight is absorbed at Earth's surface by the land, water, and vegetation. Some of this energy is emitted back from the Earth's surface in the form of infrared radiation

Explanation:

. The area of particle 1 is
2.5 mm². The area of particle 2
is 0.5 mm². The area of particle
1 is how many times as big as
the area of particle 2?​

Answers

Answer:

The correct answer is - 5 times

Explanation:

Given:

area of P1 = 2.5

area of P2 = 0.5

Solution:

Let assume:

area of P1 is x times of the area of P2

then the equation would be:

=>  2.5 = x*0.5

=>  2.5/0.5 = x

=> 5 = x

Thus, area of P1 is 5 times to the area of P2

Which of the following cells do not have specialized tasks in an organism? 1.) prokaryotic cells 2.) eukaryotic cells 3.) animal cells 4.) plant cells

Answers

Answer:

A. Prokaryotic cells

Explanation:

Prokaryotic cells don't have organelles

Need help please and thanks

Answers

Answer:

The concentration of the oxygen is higher outside of the cell and the oxygen will move inside or towards the cell since it is higher in the outside and lower inside the cell and the transport is passive and it doesn't require energy.

Particulates can be removed from smokeslack emissions by which of the following methods?

Answers

Install an electrostatic precipitator (ESP) component, which is a particle control system that helps remove particles from a smokestack by using electrical charges. According to the U.S. Environmental Protection Agency, an ESP can remove small particles with up to 99 percent efficiency.

There are three criteria that scientists use to classify kingdoms. What are they?

Answers

Answer: cell type, ability to make food, and number of cells in their body

Explanation:


In which direction will the object pictured below be accelerating?

Answers

Down as there is mor gravity than air

The condensed form of dna used for cell decision

Answers

Answer:

Chromatin

Explanation:

I'm pretty sure this is the answer, let me know if it isn't.

it would be miotic cromhatids

The vertical acis on a graph is called the y-axus for scientific data what usually placed along the y-axis

Answers

Answer:

dependent variables

pls help!!!! +10 brainly points

(I put a random answer in)

Answers

They are educated guesses is not true. A theory must be supported by evidence. Also it is mixed up with the word hypothesis in which case you could say that is an educated guess. Not for scientific theory

g The lac operon - TRUE or FALSE Before the induction of the lac operon, lactose transporters are already present in the cell membrane. TRUE Lactose initially enters the cell using a transport protein.

Answers

Answer:

True

True

Explanation:

Lactose transporter are not absent from the membrane before induction. They are already present in the cell membrane. Lactose requires some transport medium, for this reason protein acts as transport medium for the lactose.

Which word best describes the response the seedlings are shown?

Answers

Possibly Seed germination

A 14-year-old boy develops a pruritic vesicular rash on his face and hands 3 days after hiking in the woods. Which of the following are most likely to be involved in his illness?

a. Antibody, complement C5-9
b. Circulating immune complexes; complement C5a, neutrophils
c. Cytotoxic T lymphocytes
d. IgE, mast cells, histamine, cytokines
e. Lymphocytes, cytokines, macrophages

Answers

Answer:

The correct answer is: E) Lymphocytes, cytokines, macrophages.

Explanation:

Given the symptoms and how much time they took to appear, the 14-year-old boy seems to be having delayed-type hypersensitivity (also called Type 4 hypersensitivity), causing a reaction called Contact Dermatitis. Type 4 is the only type of hypersensitivity that does not require the intervening of an antibody to occur as it happens because of hapten-specific T cells that will generate inflammation and the tissue damage that is usually accompanied by it.

Delayed-type hypersensitivity is characterized for happening at least 48 hours after the contact with the antigen, and will involve activated T lymphocytes (specifically CD4+ Th1), which will secrete cytokines (most importantly Interferon Gamma and IL-2) thus attracting macrophages to the tissue to phagocyte the antigen and produce inflammation.

The dissolved waste molecules produced by the cells are removed primarily from the blood by the what?
A. large intestine
B.kidneys
C. skin
D. lungs

Answers

B-Kidneys

The kidneys act as filters that strain urea and excess salts from the bloodstream to release them in the urine.

Which statement best describes the components of nucleic acids?

Answers

Answer:

The statement which describes best about nucleic acids is: They are made up of 'nitrogen bases', 'sugars' and 'phosphates'.

Explanation: Nucleic acids are biomolecules that are known to all forms of life.

_________ is a form of spina bifida in which a saclike cyst filled with CSF protrudes through the spinal defect but does not involve the spinal cord. a. Meningomyelocele b. Meningocele c. Myelomeningocele d. Spina bifida occulta

Answers

Answer:

b. Meningocele

Explanation:

Meningocele is a congenital deformity where there is a sac protruding from the spinal column, which is not related to acute neurological conditions. Thus, meningocele is caused by a protrusion of the meninges (i.e., membranes that envelop the brain and spinal cord) and cerebrospinal fluid but without accompanying nervous tissue. About 1,500 babies each year born with this type of spinal birth defect. Moreover, spina bifida occulta is a mild type of spina bifida caused when one or more vertebrae do not fully form during pregnancy. Finally, meningomyelocele (also known as myelomeningocele) is a severe type of spina bifida caused when the spinal cord and nerves develop outside of the body.

Answer:

b. Meningocele

Explanation:

Meningocele is a form of spina bifida in which a saclike cyst filled with CSF protrudes through the spinal defect but does not involve the spinal cord.

In guinea pigs, the color of the fur is determined by a single gene with two alleles control. The brown allele (B) is dominant over the white allele (b). Two heterozygous guinea pigs are crossed. Draw a genetic diagram with the genotypic, phenotypic and ratio information of the P₁ and F ₁ generations of this cross.​

Answers

Answer:

See

Explanation:

Given:

Brown allele (B) is dominant over the white allele (b).

It will be assumed that the alleles are not related to the X and Y chromosomes.

See attached diagram for details of the general case (for both homo-zygous and hetero-zygous parents)

For both parents hetero-zygous,

P1:

Genotype: Bb (100%)

Phenotype: brown (100%)

F1:

Genotypes : BB, Bb, bB and bb in equal proportions, i.e.

BB (25%), Bb (50%), bb (25%)

Phenotypes: 75% brown (from BB and Bb), 25% white (from bb)

state the role of alcohol in this investigation​

Answers

you didn’t state the investigation we need to apply the role of alcohol to
What are the options?
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